Bujnicki lab - In the media
  • SOFTWARE
    • DATABASES
      • REPAIRtoire

        • REPAIRtoire is an online database for systems biology of DNA damage and repair. The database collects and organizes the following types of information: (i) DNA damage linked to environmental mutagenic and cytotoxic agents, (ii) pathways comprising individual processes and enzymatic reactions involved in the removal of damage, (iii) proteins participating in DNA repair and (iv) diseases correlated with mutations in genes encoding DNA repair proteins. The DNA repair and tolerance pathways are represented as graphs and in tabular form with descriptions of each repair step and corresponding proteins, and individual entries are cross-referenced to supporting literature and primary databases. In addition, a tool for drawing custom DNA-protein complexes is available online.

      • MODOMICS

        • MODOMICS is the first comprehesive database system for systems biology of RNA modification. It integrates information about the chemical structure of modified nucleosides, their localization in RNA sequences, pathways of their biosynthesis and enzymes that carry out the respective reactions (including the available protein sequence and structure data). It also provides literature information, and links to other databases. The database can be queried by the type of nucleoside (e.g. A, G, C, U, I, m1A, nm5s2U etc.), type of RNA, position of a particular nucleoside, type of reaction (e.g. methylation, thiolation, deamination, etc.), and name or sequence of an enzyme of interest. Options for data presentation include graphs of pathways involving the query nucleoside, multiple sequence alignments of RNA sequences and tabular forms with enzyme and literatiure data. The contents of MODOMICS can be accessed through the World Wide Web at http://genesilico.pl/modomics/

      • RNA Bricks

        • RNA Bricks is a database of RNA 3D structure motifs and their contacts, both with themselves and with proteins. The database provides structure-quality score annotations and tools for the RNA 3D structure search and comparison. 

      • RNArchitecture

        • RNArchitecture is a database that provides a comprehensive description of relationships between known families of structured non-coding RNAs, with a focus on structural similarities. The classification is hierarchical and similar to the system used in the SCOP and CATH databases of protein structures. Its central level is Family, which builds on the Rfam catalog, and gathers closely related RNAs. Consensus structures of Families are described with a reduced secondary structure representation. Evolutionarily related Families are grouped into Superfamilies. Similar structures are further grouped into Architectures. The highest level, Class, organizes Families into very broad structural categories, such as simple or complex structured RNAs. Some groups at different levels of the hierarchy are currently labeled as “unclassified”. For each Family with an experimentally determined 3D structure(s), a representative one is provided. RNArchitecture also presents theoretical models of RNA 3D structure and is open for submission of structural models by users. Compared to other databases, RNArchitecture is unique in its focus on structure-based RNA classification, and in providing a platform for storing RNA 3D structure predictions. RNArchitecture can be accessed at http://iimcb.genesilico.pl/RNArchitecture/.

          *The classification is expected to evolve as new data become available and we would like to encourage all interested parties to submit their suggestions for improvement as well as 3D structure predictions* 

    • STAND-ALONE
      • PROTMAP2D

        • Two-dimensional maps of contacts summarize interactions between amino acids in the structure. They reveal characteristic patterns of interactions between secondary and super-secondary structures and are very attractive for visual analysis. The overlap of the residue contact maps of two structures can be easily calculated, providing a sensitive measure of protein structure similarity. 

      • ModeRNA

        • We developed a method for 3D homology modeling of RNA structures. It requires a pairwise sequence alignment and a structural template to generate a 3D structural model of the target RNA sequence via either a fully automated or script-based approaches. ModeRNA is capable of handling 115 different nucleotide modifications and bridging gaps using fragments derived from an extensive fragment library.

      • RNAmap2D

        • RNAmap2D is a software tool for calculation of contact and distance maps based on user-defined criteria, and to some extent, quantitative comparison of pairs or series of contact maps and visualization of the results.

      • FILTREST3D

        • Filtrest3D is a program for discrimination of a large number of alternative models of protein structure or protein-ligand structure against a set of restraints derived from low-resolution experimental analyses (such as cross-linking, mutagenesis, circular dichrosm etc.) as well as from computational predictions (e.g. solvent accessibility, amino acid contact maps).

      • PyRy3D

        • PyRy3D is a software tool for modeling of structures for large macromolecular complexes. It uses Monte Carlo simulation to sample conformational space and to identify the best fit of complex components structures into a density map. Complex building process is based on distance restraints derived from experiments. 

      • Statistical potentialsRNA-Protein docking

        • We developed two medium-resolution, knowledge-based potentials for scoring protein-RNA models obtained by docking: the quasi-chemical potential (QUASI-RNP) and the Decoys As the Reference State potential (DARS-RNP). Both potentials use a coarse-grained representation for both RNA and protein molecules and are capable of dealing with RNA structures with posttranscriptionally modified residues. In our tests that compared these methods to other published potentials, DARS-RNP showed the highest ability to identify native-like structures.

      • SimRNA

        • SimRNA - a tool for simulations of RNA conformational dynamics, including RNA 3D structure prediction

      • SupeRNAlign

        • SupeRNAlign is a tool for flexible superposition of RNA 3D structures. Our program implements an iterative algorithm that splits RNA structures into fragments and superimposes them using existing tools (currently R3D Align). Finally, the superimposed structures are saved to a .pdb file and a sequence alignment is generated.

      • QRNAS

        • QRNAS is an extension of the AMBER simulation method with additional terms associated with explicit hydrogen bonds, co-planarity base pairs, backbone regularization, and custom restraints. QRNAS is capable of handling RNA, DNA, chimeras and hybrids thereof, and enables modeling of nucleic acids containing modified residues. 

    • SERVERS
      • SimRNAweb

        • SimRNAweb is a web server interface to the SimRNA method for RNA 3D structure modeling method

      • MetaServer

        • The GeneSilico MetaServer is a gateway to a number of third-party methods for protein structure prediction (identification of domains, secondary structure prediction, fold-recognition, and finally, 3D model generation). Users can submit a protein sequence (or alignment) by a single click, then analyze the summary of results generated by many methods, and finally predict the protein structure according to the "consensus" approach.

      • FILTREST3D

        • This is an "alpha" version of a server for discrimination of a large number of alternative models of protein structure against a set of restraints derived from low-resolution experimental analyses (such as cross-linking, mutagenesis, circular dichrosm etc.) as well as from computational predictions (e.g. solvent accessibility, amino acid contact maps).

      • CompaRNA

        • The CompaRNA web server provides a continuous benchmark of automated standalone and web server methods for RNA secondary structure prediction. It has been inspired by the EVA and Livebench servers for benchmarking of protein structure prediction tools, which have greatly contributed to progress in the field of structural bioinformatics. The aim of CompaRNA is to assess the state of the art in RNA structure prediction, provide a detailed picture of what is possible with the available tools, where progress is being made and what major problems remain. The CompaRNA server is a valuable resource for all researchers who focus their attention on the usage and development of RNA structure prediction methods.

      • ModeRNA server

        • ModeRNA server is an online tool for RNA 3D structure modeling by the comparative approach, based on a template RNA structure and a user-defined target-template sequence alignment. It offers an option to search for potential templates, given the target sequence. The server also provides tools for analyzing, editing and formatting of RNA structure files. It facilitates the use of the ModeRNA software and offers new options in comparison to the standalone program.

      • MetalionRNA

        • MetalionRNA is a web server for the prediction of metal ions (magnesium, sodium, and potassium) in RNA 3D structures, based on a statistical potential inferred from the analysis of binding sites observed in experimentally solved RNA structures. The server is also capable of predicting Mg2+-binding sites for DNA structures.

      • MetaLocGramN

        • The MetaGramLocN is a method for subcellular localization prediction of Gram-negative proteins. The MetaGramLocN is a gateway to a number of primary prediction methods (various types: signal peptide, beta-barrel, transmembrane helices and subcellular localization predictors). The MetaGramLocN integrates the primary methods and based on their outputs provides overall consenus prediction. To make a prediction for your protein sequence use Submit or SOAP client In our benchmark, the MetaLocGramN performed better in comparison to other SCL predictive methods, since the average Matthews correlation coefficient reached 0.806 that enhanced the predictive capability by 12% (compared to PSORTb3).

      • RIBER/DIBER

        • Co-crystallization experiments of proteins with nucleic acids do not guarantee that both components are present in the crystal. While working as a PhD student with Matthias Bochtler, Grzegorz Chojnowski developed DIBER - a method with which to predict crystal content (DNA? protein? or both?) from the diffraction data. Now, we have together developed RIBER, which should be used when protein and RNA are in the crystallization drop. The combined RIBER/DIBER suite builds on machine learning techniques to make reliable, quantitative predictions of crystal content for non-expert users and high throughput crystallography. RIBER/DIBER requires diffraction data to at least 3.0 Å resolution in MTZ or CIF format.

      • MinkoFit3D

        • MinkoFit3D is a method for fitting macromolecular assemblies or their components into electron density maps. Our approach is based on finding “tight passages” inferred from the Minkowski sum boundary of two polyhedral surfaces of the structure and its map. Following the initial fit, either a robust brute-force or a genetic algorithm is used to build an initial assembly, and multi-body refinement is applied in direct electron density space.

      • Metadisorder

        • The GeneSilico MetaServer is a gateway to a number of third-party methods for protein structure prediction (identification of domains, secondary structure prediction, fold-recognition, and finally, 3D model generation). Users can submit a protein sequence (or alignment) by a single click, then analyze the summary of results generated by many methods, and finally predict the protein structure according to the "consensus" approach.

      • QA-RecombineIT

        • QA-RecombineIt provides a web interface to assess the quality of protein 3D structure models and to improve the accuracy of models by merging fragments of multiple input models. In the first stage (QA-mode), our server predicts the global quality of input models and provides estimates of local quality as the deviation between C-α atoms in the models and corresponding atoms in the unknown native structure. Together with the input models, these predictions subsequently become the input for the second stage (RecombineIt-mode), in which fragments predicted to be better than others are judiciously combined to generate hybrid (consensus) models. Finally, hybrid models are scored by the MQAPs implemented in the QA-mode and then presented to the user

      • NPDock

        • NPDock is a web server for modeling of protein-RNA and protein-DNA complex structures. It combines GRAMM for global macromolecular docking, scoring with a statistical potential, clustering of best-scored structures, and local refinement.

      • ClaRNA

        • ClaRNA is a new method for computational classification of contacts in RNA 3D structures. Unique features of the program are the ability to identify imperfect contacts and to process coarse-grained models. Each doublet of spatially close ribonucleotide residues in a query structure is compared to clusters of reference doublets obtained by analysis of a large number of experimentally determined RNA structures, and assigned a score that describes its similarity to one or more known types of contacts, including pairing, stacking, base–phosphate and base–ribose interactions.

      • BrickworX

        • BrickworX web server builds RNA and DNA models into electron density maps at resolutions as low as 4 Å. On input the program requires a MTZ file with structure factor amplitudes and phases. 

      • GDFuzz3D

        • GDFuzz3D is a method for protein 3D structure modeling, which starts from the protein sequence and a map of contacts between amino acid residues. It can handle predicted maps that contain e.g., probabilities of contacts between all residues, and a high fraction of incorrectly predicted contacts. It is not appropriate for predicting structures based on maps with only a few predicted contacts.

      • tRNAmodpred

        • The program takes as an input a set of unmodified tRNA sequences and a set of protein sequences corresponding to a proteome of a cell, identifies all RNA residues that correspond to known modification sites with known enzymes, finds homologs of known tRNA modification enzymes, and maps the predictions onto known pathways of RNA modification, to identify theoretically possible modification reactions for all positions in query tRNAs.

      • SupeRNAlign

        • SupeRNAlign is a tool for flexible superposition of RNA 3D structures. Our program implements an iterative algorithm that splits RNA structures into fragments and superimposes them using existing tools (currently R3D Align). Finally, the superimposed structures are saved to a .pdb file and a sequence alignment is generated.

    • TOOLKIT
  • Home
  • Funded grants
    • FNP (TEAM)

      • Modeling of dynamic interactions between RNA and small molecules and its practical applications (POIR.04.04.00-00-3CF0/16-00); 3 449 541 PLN; 2017-2020. PI: J.M.Bujnicki, vice-PI: F.Stefaniak

    • NCN (MAESTRO)

      • Integrative modeling and structure determination of macromolecular complexes comprising RNA and proteins (2017/26/A/NZ1/01083); 3 500 000 PLN; 2018-2023. PI: J.M.Bujnicki, vice-PI: N.Chandran

    • NCN (MINIATURA)

      • Photoswitchable ligands for riboswitches (2018/02/X/NZ1/01468); 21670 PLN 2018-2019. PI: F.Stefaniak

    • NCN (OPUS)

      • Development of new methods for designing RNA molecules that fold into desired spatial structures and their use for development of new functional RNAs and for prediction of noncoding RNAs in transcriptome sequences (2017/25/B/NZ2/01294); 1 494 250 PLN; 2018-2021. PI: J.M.Bujnicki, vice-PI: T.Wirecki

  • Achievements
  • Publications
  • In the media
  • People
  • Employment

 

Video recordings of lectures

27.10.2015 "Restriction RNases for sequence-specific cleavage of dsRNA and RNA in DNA-RNA hybrids"
A scientific lecture (22min, in English) by prof. Bujnicki at the International Conference on Protein Engineering, October 26-28, 2015 Chicago, USA
18-20.06.2015 Video recording of the Polish Scientific Networks Conference:
1. Opening lecture by prof. Blikle
2. Concert on cello and loops
3. Official opening and discussion session (with all the VIPs!)
4. Session I: humanities and social sciences
5. Session II: science and business
6. Discussion panel: "How to strengthen relations between science and business in Poland?"
7. Session III: life sciences
8. Discussion panel: "Mobility as an element of a scientific career"
9. Session IV: hard sciences
10. Discussion panel: "Funding of research: grants vs statutory funds"
11. Discussion panel: "Models of academic careers"
12. Conference closing and summary
16.06.2015 "3D Modeling of protein-RNA complex structures"
A scientific lecture (32min, in English) at the Banff International Research Station (Canada), within the research workshop 15w5063: "Advances and Challenges in Protein-RNA: Recognition, Regulation and Prediction". 
26.03.2015  "Jak zdobywać granty?" [How to get grants?] 
A popular lecture (2h+54min, in Polish), at the Uniwersity in Białystok (Poland), about art of grantsmanship, as a part of the civic action "Więcej Dobrej Nauki" [More Good Science]

 

  Interviews and articles

12.04.2018 "Science advice for modern agricultural biotechnology" 
An interview with prof. Bujnicki (in his role as a member of the European Commission's Group of Chief Science Advisors), focused on the conclusions of the Explanatory Note on New Techniques in Agricultural Biotechnology, in particular in relation to genome editing in plants and the role of scientists in decision making. 
19.09.2017 "Ścieżki kariery" [Career pathways]
A panel discussion (in Polish), with participation of prof. Bujnicki, within the National Science Congress conference in Cracow
10.08.2017 "Trwa zacięta bitwa o prawa do technologii edycji genów CRISPR" ["An ongoing battle for intellectual property rights for the CRISPR gene editong technology"] An article in NaukawPolsce (in Polish) based on the interview with prof. Bujnicki and prof. Bochtler (both at IIMCB) about the current status and possible future of the gene editing technology from the scientific and legal points of view.
30.05.2017 "Bujnicki: nowe techniki edycji genów wciąż nie są ujęte w prawie" ["Bujnicki: new techniques for gene editing are still out of scope of the current law"]
An article in NaukawPolsce (in Polish) based on the interview with prof. Bujnicki about the current state of the so-called "new breeding techniques" with respect to the EU legislative system. The interview refers to the Explanatory Note concernig the New Breeding Techniques developed by the High Level Group of the European Commission's Scientific Advice Mechanisms (with prof. Bujnicki as one of the lead authors).
23.03.2017 "Ponad 30 naukowców apeluje: uczyńmy politykę merytoryczną!" ["More than 30 scientists appeals to make politics more evidence-based"]
An article in NaukawPolsce (in Polish) that refers to an open letter of Polish scientists (including prof. Bujnicki) to Polish politicians.
23.02.2017 "Droga do doskonałości naukowej dla polskich naukowców" [A pathway to scientific excellence for Polish scientists]
01.08.2016 "Naukowcy doradzają politykom: Bujnicki o misji wysokich doradców KE" ["Scientists advise politicians: Bujnicki about the mission of the high level advisors of the EC"] An article in NaukawPolsce (in Polish) about the role of the High Level Group of the European Commission's Scientific Advice Mechanisms, based on the interview with prof. Bujnicki, a HLG-SAM group member. 
19.07.2016 "Jak wykorzystać polski potencjał naukowy w rozwoju nowoczesnych technologii" [How to utilize Polish scientific potential for the development of new technologies]
A panel discussion (in Polish), moderated by prof. Bujnicki, within the conference "Polish Scientific Networks: Science & Business" in Wroclaw
20.04.2016 "Beneficjenci ERC: polski system nie sprzyja zdobywaniu grantów ERC" ["ERC grantees: the Polish system does not encourage the application for ERC grants"] An article in NaukawPolsce (in Polish) about the current system of science evaluation in Poland and its misalignment with the system focused on scientific excellence that underlines the European Research Council. Quotes from prof. Bujnicki as a particpant in the discussion.
05.04.2016  "Kierunki kariery młodych naukowców w Polsce" ["Career goals of junior scientists in Poland"] 
A radio interview (in Polish) with prof. Bujnicki and dr. Ajduk (head of the program committee of the Polish Scientific Networks 2016: Science and Business conference) in Polish Radio Program 1, by Krzysztof Michalski, about career paths of Polish scientists, involvement in applied research and work for or with the industry. 
23.03.2016 "Kiedy w Polsce bedziemy mieli Cambridge" ["When are we going to have Cambridge in Poland"] 
A discussion (in Polish) led by Paweł Siwek transmitted in Polish Radio Program 2, with prof. Bujnicki, dr Krystian Szadkowski and Piotr Müller, about international rankings of universities and condition of Polish system of science and higher education.
09.03.2016 "Porozmawiajmy o... (nauce)" ["Let's talk about... (science)]
A TV interview (in Polish) with prof. Bujnicki in Regional TV Warsaw (TV Warszawa), by Krzysztof Michalski, about RNA, the miraculous molecule with unique shape-shifting abilities. 
25.02.2016 "Nauka i biznes – trudna miłość z widokami na przyszłość" ["Science and busines - a difficult love with prospects"]
An article by Anna Ajduk, in Rzeczpospolita daily newspaper, about various approaches taken by scientists to commercialization of their scientific results. The article includes a number of statements from interviews with members of the Program Committee of the Polish Scientific Networks conference (second edition, 30.06-02.07.2016, focused on science-business relations), including prof. Bujnicki. 
21.02.2016 "Badania naukowe kluczem do innowacyjnej gospodarki" ["Scientific research as a key to innovative economy"]
A radio interview (in Polish) with prof. Bujnicki and dr. Krasiński (director of the National Contact Point) in Polskie Radio 24, by Grzegorz Frątczak, about the condition of Polish scientific institutions and about cooperation between the academia and the industry. 
02.02.2016 "Więcej dobrej nauki" ["More good science"]
An interview with prof. Bujnicki by Krzysztof Bielski and Aleksandra Kwika in Oblicza Neuronauki ["Faces of Neuroscience"] (in Polish, issue 5, pages 6-9), about his career pathway, activity in the Citizens of Science movement, grant writing and the "More Good Science" action, and about ideas for improving the science-funding system in Poland. 
10.11.2015 Press releases and news concerning the selection of prof. Janusz Bujnicki as a member of the first High Level Group of scientific advisors within the European Commission's new Scientific Advice Mechanism (SAM):
- European Commission Research & Innovation News Alert
- Polish Academy of Sciences (in Polish)
- Polish Press Agency (in Polish) 
29.07.2015  "Życia Uniwersytetu - odcinek 171 / Prof. Janusz Bujnicki – młodość w bioinformatyce" ["University Life - part 171 / Prof. Janusz Bujnicki - youth in bioinformatics"]  - a TV interview with prof. Bujnicki (in Polish) for the Adam Mickiewicz University video magazine (00:03:00-00:05:48)
05.2015 "Modelowy wynalazca
" ["Model inventor"]
An article by Mariusz Karwowski
 in Forum Akademickie (in Polish) based on an interview with prof. Bujnicki, about his work on RNA and RNA_interacting proteins, and about inspiration from dadaism that prompt new scientific projects.
21.05.2015  "Mafia naukowa' z polskim rodowodem" ["Scientific mafia" of Polish origin]
A radio interview (in Polish) with prof. Bujnicki in Polskie Radio 24, by Krzysztof Michalski, about the world-wide network of Polish structural biologists and bioinformaticians, as well as about Bujnicki's recent discovery of a ribonuclease that can cut RNA sequence-specifically, like restriction enzymes that cut DNA.
13.05.2015 "Porozmawiajmy o... (nauce)" ["Let's talk about... (science)]
A TV interview (in Polish) with prof. Bujnicki and prof. Joanna Trylska (CeNT UW) in Regional TV Warsaw (TV Warszawa), by Krzysztof Michalski, about the Multipole-2 conference [http://multipole-meetings.org/], about Polish crystallographers and bioinformaticians and about efforts to strengthen interdisciplinary and transatlantic collaboration in structural biosciences.
03.2015 "Co jest najważniejsze w nauce" ["What is most important in science"]
An interview with prof. Bujnicki by Jadwiga Dąbrowska in Kwartalnik Urzędu Patentowego RP ["Quarterly review of Polish Patent Office"] (in Polish, issue 2/2015, pages 12-16), about inspirations, creativity, innovations resulting from basic research, and importance of popularization of science.
14.02.2015 "Prof. Janusz Bujnicki i odkrycie "nożyczek" do cięcia dwuniciowego RNA" ["Prof. Janusz Bujnicki and the discovery of "scissors" for cleavage of double-stranded RNA"] - an interview with prof. Janusz Bujnicki in the "Homo science" program in the TOK FM radio station (in Polish) about his team's latest achievement and about various other issues, from RNA and nanotechnology to bioinformatics, distributed computing and citizen science. 
16.10.2014 "Nagroda Narodowego Centrum Nauki 2014" ["Award of the National Science Center"] - prof. Janusz Bujnicki 
Prof. Bujnicki speaks (in Polish) about his and his team's achievements in research, awarded by the National Science Center with the NCN Prize in Life Sciences.
11.10.2014 "Zawód Naukowiec" ["Occupation Scientist"] 
A movie comprising interviews (in Polish) with 11 "ambassadors of science" (including prof. Bujnicki) as a part of a promotional campaign of Polish Ministry of Science and Higher Education.
19.09.2014 "MISTRZ - prof. Janusz. Bujnicki"
An interview (in Polish) with Prof. Bujnicki, for Radio Kampus, about his MISTRZ (MASTER) award from the Foundation for Polish Science.
03.09.2014 "Popularyzacja nauki jest naszym obowiązkiem" ["Popularizing science is our duty"]
An interview (in Polish) with Prof. Bujnicki, in the "Teraz Polska" magazine (pages 44-47), about communication of scientists with society, including the general public, business, and governmental and non-governmental organizations. 
07.08.2014 "Masz szerokie zainteresowania i ciekawość świata? Będziesz świetnym naukowcem"
["Do you have broad interests and curiosity about the world? You will make a great scientist"]
Prof. Bujnicki speaks (in Polish) about being a scientist - as a job and as a way of life. Recording made as a part of Gazeta Wyborcza's "project: occupation" ("projekt: praca") 
13.05.2014 "IV Młodzi Innowacyjni" ["Young Enterpreneurs Forum IV"]: Janusz Bujnicki 
An interview (in Polish) with Prof. Bujnicki, about the need for strengthening creativity in education in Poland, made during the Young Enterpreneurs Forum in Warsaw.
18.02.2014 "Najlepiej zacząć od własnego podwórka" ["Start working in your own backyard"] 
An interview (in Polish) with Prof. Bujnicki, following his award in the Science category of "Poles with verve" plebiscite organized by PKN ORLEN.
29.01.2014 Janusz Bujnicki and Marcin Nowotny in "Porozmawiajmy o..." ["Let's talk about..."]
A TV interview (in Polish) with prof. Bujnicki and dr. Nowotny in Regional TV Warsaw (TV Warszawa), by Krzysztof Michalski, about their recent joint publication in Nature Communications and about challenges on the interface of basic and applied research
20.01.2014 "Metylotransferazy" ["Methyltransferases"]
An interview (in Polish) with prof. Bujnicki and dr. Nowotny in the Polish Radio Programme 1, by Krzysztof Michalski, about their recent analysis of human methyltransferases CMTr1 and CMTr2 published in Nature Communications ("Naukowy Zawrót Głowy" ["Scientific Vertigo"])
09.01.2014 "Polscy naukowcy ustalili struktury przestrzenne i mechanizm działania metylotransferaz!"
["Polish scientists determined three-dimensional structures and mechanism of actions of methyltransferases"]
Press release concerning the newly published article in Nature Communications (Smietanski et al. 2014), about the work on CMTr1 and CMTr2 methyltransferases done by the Bujnicki group in collaboration with the Nowotny group and Darzynkiewicz group.
29.12.2013 Janusz Bujnicki in "Inny Punkt Widzenia" ["Different Point of View"]
An interview (in Polish) with Prof. Bujnicki, by Grzegorz Miecugow
24.10.2013 "Bakterie, komputery i dadaizm" ["Bacteria, computers and dadaism"]
An interview (in Polish) with Prof. Bujnicki, about his research interestes and inspirations in art. Interview in the series "Nie tylko Skłodowska" ["Not only Sklodowska"].
01.09.2013 "Bioinformatyką w antybiotykooporność" ["Bioinformatics against antibiotic resistance"]
An interview (in Polish) with Prof. Bujnicki, about his research towards the discovery of chemical compounds that could abolish bacterial resistance against antibiotics.
21.04.2013 "Lider zespołu badawczego - naukowiec i menedżer w jednym" ["Research group leader - a scientist and a manager"] and
"Jak skutecznie aplikować o granty ERC?" ["How to apply successfully for ERC grants?"]
A video interview (in Polish) with Prof. Bujnicki, about his work as a group leader and about grant writing.
04.04.2013 "Leki przyszłości z grantów ERC" ["Drugs of the future from ERC grants"]
An interview (in Polish) with Prof. Bujnicki, about his early inspirations, current projects focused on RNA research, and plans for the future in the area of RNA nanotechnology.
08.03.2013 "Prof. Bujnicki wie, jak zdobywać prestiżowe unijne granty" ["Prof. Bujnicki knows how to win prestigious EU grants"]
An article (in Polish) based on an interview with prof. Bujnicki, about his experience with grant-writing and learning from failures.
03.03.2013 "The ERC, where dreams come true"
Video (in English) by the European Research Council with the participation of Prof. Janusz Bujnicki as one of Polish awardees of ERC grants.
01.03.2013 "Programy komputerowe pomagają zrozumieć RNA" ["Computer programs help us understand RNA"]
An article (in Polish) based on an interview with prof. Bujnicki, about his recent projects funded by the European Research Council: Starting Grant "RNA+P=123D: Breaking the code of RNA sequence-structure-function relationships: New strategies and tools for modelling and engineering of RNA and RNA-protein complexes" and Proof of Concept Grant "Engineered sequence-specific RNases: New reagents for RNA biotechnology"
20.02.2012 "Życie jest formą istnienia białka" ["Life is a form of protein existence"]
An interview (in Polish) with prof. Bujnicki and dr. Nowotny (head of Laboratory of Protein structure in IIMCB) in the Polish Radio Programme 1, about the importance of studies of protein structure ("Evening of Discoveries")
21.11.2011 "Ojcowie chrzestni polskiej mafii bioinformatycznej" ["Godfathers of Polish bioinformatics mafia"]
An interview (in Polish) with prof. Bujnicki, together with prof. Filipowicz and prof. Wlodawer (members of the IIMCB International Advisory Board), and prof. Minor in the Polish Radio Programme 1, about protein (and RNA!) structure determination and prediction ("Evening of Discoveries")
25.04.2007 "Nagrody za prace nad komputerowym modelowaniem białek" ["Awards for work on computer modeling of proteins"]
An article (in Polish) based on an interview with prof. Bujnicki, about protein structure prediction, enzymes that modify RNA, and identification of small molecules - candidates for new drugs.