Bujnicki lab - Employment

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Laboratory of Bioinformatics and Protein Engineering at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw, headed by Prof. Janusz M. Bujnicki, offers a position for a


Postdoctoral Researcher
in software development for crosslinking-based stabilization of proteins: collaboration between the academia and the industry

 
Deadline for applications: September 18th, 2022. Preferred job starting date: November 2nd, 2022 or as soon as possible

As a Postdoctoral Researcher, you will play a leading role in the development of software for computational design of chemical cross-linking strategies that aim for stabilization of protein 3D structures for for biotechnological and biomedical applications. In particular, you will be involved in the development of new software, optimization of existing software, in the design and optimization of computational workflows. The goal of your work will be to develop and test software for the development of improved protein variants that have real-life application in biotechnology.

This position is funded by a prestigious TRANSITION grant INCYPROnext from the European Innovation Council, which supports bilateral collaboration between Incircular B.V., a spin-off founded by the Vrije Universiteit Amsterdam (coordinator), and the International Institute of Molecular and Cell Biology in Warsaw (academic collaborator).The project aims to improve and commercialize INCYPRO, the innovative protein stabilization technology invented and developed in Prof. Grossman's research lab at VUA, with the macromolecular modeling expertise of Prof. Bujnicki's lab at IIMCB. The Grossman and Bujnicki teams have already collaborated scientifically and published a joint paper. The goal of the INCYPROnext grant is to provide a key technology for stabilizing proteins in therapeutics and diagnostics that will enable applications that were not previously possible. 

We offer:
• Full-time contract (“umowa o pracę”) for at least 12 months, with an intended extension depending on performance and applications for extramural funding 
• Gross monthly remuneration starting at 12,000 PLN/month, net approx. 9,000 PLN/month, commensurate with experience (the final monthly gross salary will be calculated individually during the employment process, taking into account the length of service). Additional bonuses such as the 13th salary after working for the Institute for six months in a given calendar year, or Christmas bonus may supplement this salary.
• Benefits including reduced-rate for an individual medical care package and membership in the MultiSport program
• Work in a multidisciplinary, international team, in a very dynamic organization, with multiple opportunities for professional development, participation in courses, scientific training, support from peers, and academic mentoring
• Administrative and organizational support from professional English-speaking personnel 

We require:
• Ph.D. in any area relevant to the project (e.g., structural biology, physics, biology, chemistry, etc.)
• Strong publication record, including at least one first-author publication in a very good journal 
• Documented experience in molecular simulations 
• Documented experience in programming: C/C++ is a must, Python is highly advantageous
• Experience in structural bioinformatics is not essential, but will be a strong advantage
• Experience in machine learning is not essential, but will be a strong advantage
• Expertise and competence in designing and carrying out computational analyses of complex datasets and in interpreting their results
• Experience in writing manuscripts for publication, and fellowship or grant proposals
• Vision of your professional growth within ~3-5 years, including the capacity to apply for fellowship/grant funding within the first year of your employment, with projects that synergize the core strengths of the team with your own ideas 
• Proactive approach to achieving objectives, good interpersonal skills, collaborative and adaptive attitude
• Very good organizational skills, especially project and time management skills• Very good command of English (written and oral communication) and presentation skills 

How to apply: 
• Email your application to recruitment@iimcb.gov.pl 
• In the subject of the message include "IIMCB-researcher-INCYPRO" and your first and last name• Your application must be submitted in English and should contain: 1) a CV, 2) a cover letter including a short description of your key achievements and explicit responses to the following questions: What are your scientific interests and how do they relate to requirements of the position offered? What are your key strengths? What do you know about our laboratory, why do you want to work with us, what would you like to learn while working with us?, 3) contacts to at least two potential referees, including your Ph.D. supervisor. At this stage, please do not attach copies of diplomas, etc. 
• Please include the following statement in your CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.” Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the link https://bit.ly/3guEMJ7
• We will contact only selected best candidates, who may be given additional questions and tasks as a part of the recruitment process• The competition may be extended or repeated until a suitable candidate who fulfills all requirements is found

The Postdoctoral Researcher will be selected from candidates in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy https://bit.ly/35tXdaq .

Research Specialist Position

lab technician for biochemistry of RNA and proteins complexes

 

Deadline for applications: November 30th, 2022. Preferred job starting date: January 1st, 2023 or as soon as possible

 

As a Research Specialist, you will support the team in research activities, from experiment design to the interpretation of results. You will be expected to master a wide range of techniques including RNA expression and purification, biochemical assays, structural analyses (including crystallization), and analyzing molecular interactions with various biochemical and biophysical techniques. You will be also involved in the support of processes in the experimental part of our lab, including house-keeping, ordering supplies, maintaining stocks, taking care of documentation, organizing lab protocols, etc.

 

The position is ideal for you if you love experimental biochemistry, if you are organized and adaptive, and if you enjoy teamwork. We want you at this position if you have the drive to learn and implement new experimental methods, and if you are comfortable with multitasking and being involved in multiple projects in parallel. You will have an opportunity to contribute to scientific publications as a co-author.

 

We offer:

• Full-time contract (“umowa o pracę”) initially for a trial period (three months), with an intended long-term extension

• Gross salary starting at ~6100 PLN/month with social security.  Additional 13th salary after working a minimum of six months in a given calendar year

• Benefits including reduced-rate for an individual medical care package and membership in the MultiSport program

• Scientific training, support from peers

• Administrative and organizational support from professional English-speaking personnel

 

We require:

• M.Sc. or Ph.D. in biochemistry, molecular biology, or related discipline

• Expertise and technical competence in designing and conducting scientific experiments and in interpreting their results

• Very good organizational skills, p approach to achieving objectives, collaborative and adaptive attitude

• Very good command of English (written and oral communication) and at least good command of Polish

• Documented experience in protein or RNA biochemistry will be advantageous, but is not essential

• Experience in lab management and/or in supervising junior scientists will be advantageous, but it not essential

 

How to apply:

• Email your application to recruitment@iimcb.gov.pl  

• In the subject of the message include " IIMCB-technician-biochemistry " and your first and last name

• application must be submitted in English and should contain: 1) a CV, 2) a cover letter including a short description of key achievements and explicit responses to the following questions: What are scientific interests and how do they relate to requirements of the position offered? What are key strengths? What do know about our laboratory and why do want to work with us?, 3) contacts to at least two potential referees, including Ph.D.) . At this stage, please do not attach copies of diplomas, .

• Please include the following statement in CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.” data will the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the link https://bit.ly/3FHhblE

• We will contact only selected best candidates, who may be given additional questions and tasks as a part of the recruitment process

• The competition may be extended or repeated until a suitable candidate who fulfills all requirements is found

 

The Research Specialist will be selected from candidates in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy https://bit.ly/3TacmV2

 

PhD student position

in modeling of RNA structure and RNA-protein complexes

 

Deadline for applications: November 20st 2022. Preferred job starting date: December 1st, 2022

 

A PhD position is offered within a project entitled “Integrative modeling and structure determination of RNA-protein complexes” carried out as the MAESTRO grant of the Polish National Science Centre (2017/26/A/NZ1/01083).
The grant (and the associated funding) is expected to conclude in 2023. Therefore, we offer this positions for 7 months, to PhD candidates who are already enrolled in (or eligible to be enrolled to) the 3rd or 4th year of PhD studies in Poland and able to carry out research and complete the PhD project, and defend the PhD thesis not later than December 31st 2023, under the supervision of prof. Bujnicki. All candidates from Poland or abroad who fulfill formal requirements are encouraged to apply.

 

As a PhD student, you will be involved in research focused on the development and applications of new computational techniques for the structure prediction of RNA molecules and RNA-protein complexes. This position is ideal for you have experience in RNA bioinformatics, very good programming skills in C/C++ and Python, and if you have already advanced your PhD project related to the structural bioinformatics of RNA to at least 50%.

 

 

We offer:

• PhD fellowship of 4000 PLN (gross remuneration) for 7 months

• Benefits including reduced-rate for an individual medical care package and membership in the MultiSport program

• Work in a multidisciplinary, international team, in a very dynamic organization, with multiple opportunities for professional development, participation in courses, scientific training, support from peers, and academic mentoring

• Administrative and organizational support from professional English-speaking personnel

 

We require:

• Fulfillment of formal criteria of the competition in particular section 2.1.3: https://bit.ly/3WrMiHH

• Enrollment in a Ph.D. study in one of the Polish institutions of science and higher education, in the area of biological sciences, at the 3rd or 4th year of the studies.

• Doctoral project advanced to at least 50% and eligibility to defend the Ph.D. until December 2023 at the latest, and preferably earlier

• Ability to devote 100% of time to the work on the project

• Eligibility to have prof. Bujnicki as the sole doctoral advisor and the sole supervisor

• Experience and documented results in development of software for structural bioinformatics of RNA

• Documented experience in programming (C/C++ and Python) – the application must include samples of the code in all these languages or links to repositories from which the software can be obtained

• Good command of English (written and oral communication) and presentation skills

• Priority will be given to candidates with results that can be included in the Ph.D. thesis and with expertise most relevant to the project

 

How to apply:

• Email your application to recruitment@iimcb.gov.pl

• In the subject of the message include "MAESTRO-PhD-student-RNAstructureprediction" and your first and last name

• application must be submitted in English and should contain: 1) a CV, 2) a cover letter including a short description of key achievements and explicit responses to the list of requirements.

• Please include the following statement in CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.” data will the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the link https://bit.ly/3FHhblE

• We will contact only selected best candidates, who may be given additional questions and tasks as a part of the recruitment process

• The competition may be extended or repeated until a suitable candidate who fulfills all requirements is found

 

The Ph.D. students will be selected from candidates in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy https://bit.ly/3TacmV2

 

 


  

 

„Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Research Council. Neither the European Union nor the granting authority can be held responsible for them.”