First Author	Title	Journal Title	PubMed ID / DOI
Hausmann S	Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).	J Biol Chem	16046409
Urbonavicius J	Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implications.	Nucleic Acids Res	16027442
Marmier-Gourrier N	A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA.	RNA	12810916
Hager J	Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.	J Bacteriol	15375145
Sunita S	Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC.	Nucleic Acids Res	17576679
Kolodrubetz D	Sequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae.	Yeast	2063628
Motorin Y	Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.	RNA	10445884
Walbott H	Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase.	RNA	17475914
Motorin Y	The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity.	RNA	9671058
Behm-Ansmant I	The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.	RNA	14561887
Grosjean H	Aminoacylation of the anticodon stem by a tRNA-synthetase paralog: relic of an ancient code?	Trends Biochem Sci	15450604
Behm-Ansmant I	The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase.	RNA	17684231
Kotelawala L	Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species.	RNA	18025252
Ikeuchi Y	The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.	EMBO J	18668122
Kambampati R	IscS is a sulfurtransferase for the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA.	Biochemistry	10600118
Bujnicki JM	Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family.	J Mol Microbiol Biotechnol	12125821
Purushothaman SK	Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA.	Mol Cell Biol	15899842
Hamilton CS	Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine.	Biochemistry	17002302
Bujnicki JM	Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m(6)A methyltransferase.	J Mol Evol	12355263
de Beus E	Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker.	J Cell Biol	7806561
Wolfe MD	Functional diversity of the rhodanese homology domain: the Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2-selenouridine synthase.	J Biol Chem	14594807
Jiang W	An essential yeast protein, CBF5p, binds in vitro to centromeres and microtubules.	Mol Cell Biol	8336724
Salazar JC	A truncated aminoacyl-tRNA synthetase modifies RNA.	Proc Natl Acad Sci U S A	15096612
Pierrel F	MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.	J Biol Chem	15339930
Roovers M	A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase.	Nucleic Acids Res	14739239
Hallberg BM	The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain.	J Mol Biol	16793063
Pintard L	MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase.	EMBO J	11867542
Caldas T	The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase.	J Biol Chem	10748051
Hausmann S	Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1).	J Biol Chem	15590684
Frey B	New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium.	J Bacteriol	3129401
Wrzesinski J	Purification, cloning, and properties of the 16S RNA pseudouridine 516 synthase from Escherichia coli.	Biochemistry	7612632
Mouaikel J	Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus.	Mol Cell	11983179
Romanowski MJ	Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.	Proteins	12001236
Cabedo H	The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties.	EMBO J	10601028
Clery A	Analysis of sequence and structural features that identify the B/C motif of U3 small nucleolar RNA as the recognition site for the Snu13p-Rrp9p protein pair.	Mol Cell Biol	17145781
Jacq C	The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.	Nature	9169867
Kato T	A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.	Cancer Res	15994936
Watanabe M	Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain.	J Biol Chem	9242689
Lapeyre B	Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage.	Mol Cell	15546625
Pintard L	Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.	EMBO J	11927565
Agarwalla S	Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.	J Biol Chem	11779873
Massenet S	Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.	Mol Cell Biol	10022901
Hagervall TG	Genetic mapping and cloning of the gene (trmC) responsible for the synthesis of tRNA (mnm5s2U)methyltransferase in Escherichia coli K12.	Mol Gen Genet	6387395
Lesnyak DV	Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.	J Biol Chem	17189261
Kalhor HR	Novel methyltransferase for modified uridine residues at the wobble position of tRNA.	Mol Cell Biol	14645538
Grimm C	Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase.	Biochem Biophys Res Commun	17083917
Noma A	Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.	EMBO J	16642040
Bonnerot C	Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast.	Mol Cell	14636587
Decoster E	MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase.	J Mol Biol	8392589
Gu XR	Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli.	Biochemistry	10194318
Del Campo M	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli.	RNA	11720289
Slany RK	A new function of S-adenosylmethionine: the ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine.	Biochemistry	8347586
Soma A	An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.	Mol Cell	14527414
De Bie LG	The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.	J Bacteriol	12730187
Brisson-Noel A	Evidence for natural gene transfer from gram-positive cocci to Escherichia coli.	J Bacteriol	2832378
Michel G	The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot.	Structure	12377117
Watanabe K	Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes.	J Biol Chem	16963456
Gutgsell N	Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells.	RNA	11142385
Jager G	The conserved Cys-X1-X2-Cys motif present in the TtcA protein is required for the thiolation of cytidine in position 32 of tRNA from Salmonella enterica serovar Typhimurium.	J Bacteriol	14729701
Bujnicki JM	Sequence-structure-function studies of tRNA:m5C methyltransferase Trm4p and its relationship to DNA:m5C and RNA:m5U methyltransferases.	Nucleic Acids Res	15121902
Hagervall TG	Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities.	J Biol Chem	3298234
Stengl B	Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism.	Chembiochem	16206323
Bussey H	The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.	Nature	9169875
Calvo O	GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae.	Mol Cell Biol	10330157
Tsukamoto T	Isolation and characterization of the yeast mRNA capping enzyme beta subunit gene encoding RNA 5'-triphosphatase, which is essential for cell viability.	Biochem Biophys Res Commun	9345280
Lauhon CT	Substitutions in an active site loop of Escherichia coli IscS result in specific defects in Fe-S cluster and thionucleoside biosynthesis in vivo.	J Biol Chem	14978044
Gutgsell NS	A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain.	RNA	11453071
Kressler D	Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae.	Nucleic Acids Res	10556316
Toh SM	The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA.	RNA	18025251
Lesnyak DV	Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA.	J Mol Biol	17010378
Yim L	The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.	J Biol Chem	12730230
Wolf J	tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.	EMBO J	12110595
Wu P	Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast.	J Biol Chem	9632712
Watanabe K	Roles of conserved amino acid sequence motifs in the SpoU (TrmH) RNA methyltransferase family.	J Biol Chem	15637073
Caillet J	Molecular cloning of the Escherichia coli miaA gene involved in the formation of delta 2-isopentenyl adenosine in tRNA.	J Bacteriol	3045085
Waas WF	Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.	J Biol Chem	16162496
Gutgsell NS	The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli.	RNA	15928344
Lauhon CT	Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli.	J Bacteriol	12446632
Hopper AK	tRNA transfers to the limelight.	Genes Dev	12533506
Baker DL	RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP.	Genes Dev	15870259
Gustafsson C	Identification of the rrmA gene encoding the 23S rRNA m1G745 methyltransferase in Escherichia coli and characterization of an m1G745-deficient mutant.	J Bacteriol	9440525
Leinfelder W	In vitro synthesis of selenocysteinyl-tRNA(UCA) from seryl-tRNA(UCA): involvement and characterization of the selD gene product.	Proc Natl Acad Sci U S A	2405383
Basturea GN	Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.	RNA	16431987
Mathews I	Crystal structure of S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold.	Proteins	15822125
Ny T	Cloning and restriction mapping of the trmA gene coding for transfer ribonucleic acid (5-methyluridine)-methyltransferase in Escherichia coli K-12.	J Bacteriol	6247318
Nordlund ME	Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae.	RNA	10864043
Appel CD	Structural features of the guide:target RNA duplex required for archaeal box C/D sRNA-guided nucleotide 2'-O-methylation.	RNA	17438123
Xing F	The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs.	J Biol Chem	14970222
Rozenski J	The RNA Modification Database: 1999 update.	Nucleic Acids Res	9847178
Swairjo MA	Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme.	Acta Crystallogr Sect F Struct Biol Cryst Commun	16511203
Campanacci V	The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.	J Mol Biol	15003446
Bishop AC	Identification of the tRNA-dihydrouridine synthase family.	J Biol Chem	11983710
Gerber AP	An adenosine deaminase that generates inosine at the wobble position of tRNAs.	Science	10550050
Nakanishi K	Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.	Proc Natl Acad Sci U S A	15894617
Tettelin H	The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.	Nature	9169869
Hamma T	The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.	Nat Struct Mol Biol	16286935
Blaise M	Glu-Q-tRNA(Asp) synthetase coded by the yadB gene, a new paralog of aminoacyl-tRNA synthetase that glutamylates tRNA(Asp) anticodon.	Biochimie	16164993
Yim L	Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.	Nucleic Acids Res	17062623
Lee TT	A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function.	Cell	15766524
Cupp-Vickery JR	Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli.	J Mol Biol	15050828
Nasvall SJ	The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.	RNA	15383682
Philippsen P	The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.	Nature	9169873
Esberg B	Identification of the miaB gene, involved in methylthiolation of isopentenylated A37 derivatives in the tRNA of Salmonella typhimurium and Escherichia coli.	J Bacteriol	10572129
Ollagnier-de-Choudens S	Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin.	J Biol Chem	11319236
Bujnicki JM	Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus.	J Mol Microbiol Biotechnol	11763974
Henras A	Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.	EMBO J	9843512
Girard JP	GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast.	EMBO J	1531632
Purta E	Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.	Proteins	15789416
Alexandrov A	Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.	RNA	12403464
Zhang X	The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation.	RNA	16601205
Hellmuth K	Cloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p.	Nucleic Acids Res	11095668
Ozanick S	The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.	RNA	16043508
Ansmant I	Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi(2819) in 21S mitochondrial ribosomal RNA.	Nucleic Acids Res	10756195
Bujnicki JM	In silico analysis of the tRNA:m1A58 methyltransferase family: homology-based fold prediction and identification of new members from Eubacteria and Archaea.	FEBS Lett	11684083
Anderson J	The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.	Genes Dev	9851972
Wilkinson ML	The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.	RNA	17242307
Bujnicki JM	Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases.	FASEB J	11053259
Bystrom AS	The structural gene (trmD) for the tRNA(m1G)methyltransferase is part of a four polypeptide operon in Escherichia coli K-12.	Mol Gen Genet	6298574
Dong X	Crystal structure of tRNA pseudouridine synthase TruA from Thermus thermophilus HB8.	RNA Biol	17114947
Suzuki Y	Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA.	J Mol Biol	17727881
Motorin Y	Transfer RNA recognition by the Escherichia coli delta2-isopentenyl-pyrophosphate:tRNA delta2-isopentenyl transferase: dependence on the anticodon arm structure.	RNA	9214656
Astrom SU	Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination.	Cell	7954819
Bjork GR	Genetic dissection of synthesis and function of modified nucleosides in bacterial transfer RNA.	Prog Nucleic Acid Res Mol Biol	7538683
Pan H	The crystal structure of E. coli rRNA pseudouridine synthase RluE.	J Mol Biol	17320904
Dubois DY	An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp.	Proc Natl Acad Sci U S A	15096594
Soderberg T	Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop.	Biochemistry	10828971
Lafontaine D	The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.	Genes Dev	7590228
Hur S	How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA.	Mol Cell	17466622
Schubot FD	Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription.	Protein Sci	11567089
Anderson J	The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae.	Proc Natl Acad Sci U S A	10779558
Dihanich ME	Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae.	Mol Cell Biol	3031456
Kaya Y	A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.	RNA	12756329
Kalhor HR	Protein phosphatase methyltransferase 1 (Ppm1p) is the sole activity responsible for modification of the major forms of protein phosphatase 2A in yeast.	Arch Biochem Biophys	11697862
Roovers M	Formation of the conserved pseudouridine at position 55 in archaeal tRNA.	Nucleic Acids Res	16920741
Bujnicki JM	Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases.	Acta Microbiol Pol	11518396
Vaidyanathan PP	RluD, a highly conserved pseudouridine synthase, modifies 50S subunits more specifically and efficiently than free 23S rRNA.	RNA	17872507
Kolman C	SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing.	J Bacteriol	8444805
Johansson MJ	The Saccharomyces cerevisiae TAN1 gene is required for N4-acetylcytidine formation in tRNA.	RNA	15037780
Bugl H	RNA methylation under heat shock control.	Mol Cell	10983982
McCleverty CJ	Crystal structure of human Pus10, a novel pseudouridine synthase.	J Mol Biol	17900615
Basturea GN	Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE.	RNA	17872509
Taylor AB	The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.	Nucleic Acids Res	18208838
Persson BC	The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity.	Nucleic Acids Res	9321663
Leipuviene R	Formation of thiolated nucleosides present in tRNA from Salmonella enterica serovar Typhimurium occurs in two principally distinct pathways.	J Bacteriol	14729702
Wachino J	Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.	Antimicrob Agents Chemother	17875999
Pintard L	Spb1p is a yeast nucleolar protein associated with Nop1p and Nop58p that is able to bind S-adenosyl-L-methionine in vitro.	Mol Cell Biol	10648622
Behm-Ansmant I	Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.	J Biol Chem	15466869
Kambampati R	MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli.	Biochemistry	12549933
Andersen NM	YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407.	J Mol Biol	16678201
Purta E	YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.	RNA	18755835
Matte A	Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.	Acta Crystallogr Sect F Struct Biol Cryst Commun	16511038
Okamoto S	Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.	Mol Microbiol	17238915
Teplova M	The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.	Protein Sci	11206077
Caldas T	Translational defects of Escherichia coli mutants deficient in the Um(2552) 23S ribosomal RNA methyltransferase RrmJ/FTSJ.	Biochem Biophys Res Commun	10814528
Conrad J	The rluC gene of Escherichia coli codes for a pseudouridine synthase that is solely responsible for synthesis of pseudouridine at positions 955, 2504, and 2580 in 23 S ribosomal RNA.	J Biol Chem	9660827
Carnahan RH	Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.	Eukaryot Cell	15755920
Cupp-Vickery JR	Crystal structure of IscS, a cysteine desulfurase from Escherichia coli.	J Mol Biol	12860127
Xing F	A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.	RNA	12003496
Kalhor HR	A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.	Biochem Biophys Res Commun	16005430
Cavaille J	The yeast Saccharomyces cerevisiae YDL112w ORF encodes the putative 2'-O-ribose methyltransferase catalyzing the formation of Gm18 in tRNAs.	RNA	9917067
Elkins PA	Insights into catalysis by a knotted TrmD tRNA methyltransferase.	J Mol Biol	14583191
Purta E	The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.	BMC Mol Biol	16848900
Na JG	Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae.	Genetics	1325384
Sergiev PV	The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.	J Mol Biol	18021804
Bjork GR	A primordial tRNA modification required for the evolution of life?	EMBO J	11226173
Colby G	MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae.	J Biol Chem	9774408
Matsumoto K	RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8-Trm82 complex).	FEBS Lett	17382321
Tomoyasu T	The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression.	J Bacteriol	8444796
Reuter K	Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes.	J Bacteriol	1706703
Madsen CT	Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry.	Nucleic Acids Res	12907714
Pan H	Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit.	Proc Natl Acad Sci U S A	14566049
Hong B	Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast.	Mol Cell Biol	8972218
Reynaud A	Disruption and functional analysis of six ORFs of chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1).	Yeast	11180460
Tkaczuk KL	Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases.	BMC Bioinformatics	17338813
Clancy MJ	Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene.	Nucleic Acids Res	12384598
Mueller EG	Identification of a gene involved in the generation of 4-thiouridine in tRNA.	Nucleic Acids Res	9592144
Jablonowski D	tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin-induced cell death in yeast.	Mol Microbiol	16390459
Lecointe F	Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.	J Biol Chem	9430663
Hager J	Active site in RrmJ, a heat shock-induced methyltransferase.	J Biol Chem	12181314
Mathevon C	tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase.	Proc Natl Acad Sci U S A	17679698
Sirum-Connolly K	Functional requirement of a site-specific ribose methylation in ribosomal RNA.	Science	8266080
Hong B	Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.	Nucleic Acids Res	11452018
Sergiev PV	Ribosomal RNA guanine-(N2)-methyltransferases and their targets.	Nucleic Acids Res	17389639
Mao X	Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.	Mol Cell Biol	7623811
Bujnicki JM	mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships.	BMC Bioinformatics	11472630
Hagervall TG	Reduced misreading of asparagine codons by Escherichia coli tRNALys with hypomodified derivatives of 5-methylaminomethyl-2-thiouridine in the wobble position.	J Mol Biol	9811540
Monleon D	Structural insights into the GTPase domain of Escherichia coli MnmE protein.	Proteins	17143896
Nilsson K	The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium.	J Bacteriol	12446633
Hoang C	Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold.	RNA	15208439
Bujnicki JM	Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.	RNA	15247431
White J	Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.	Mol Cell Biol	18332120
Wrzesinski J	A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for psi 746 in 23S RNA is also specific for psi 32 in tRNA(phe).	RNA	7493321
Lee TT	Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase.	Structure	15016356
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Nate J Fry	N-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.	Oncotarget	30131850
Chuanzhao Zhang	Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.	Proc Natl Acad Sci U S A	27001847
Lianpin Wu	Changes of N6-methyladenosine modulators promote breast cancer progression.	BMC Cancer	30953473
Yi Niu	RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.	Mol Cancer	30922314
Carolyn M Klinge	HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells.	Sci Rep	31263129
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Shun Zhou	FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation.	Mol Carcinog	29315835
Dongling Zou	The mA eraser FTO facilitates proliferation and migration of human cervical cancer cells.	Cancer Cell Int	31827395
Xiuli Wang	Reduced mA mRNA methylation is correlated with the progression of human cervical cancer.	Oncotarget	29228737
Chen W	A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer.	Oncotarget	28455960
Qingfei Jiang	ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.	Proc Natl Acad Sci U S A	23275297
Ru Deng	mA methyltransferase METTL3 suppresses colorectal cancer proliferation and migration through p38/ERK pathways.	Onco Targets Ther	31239708
Chen X	METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-DependentPrimary miR-375 Processing.	Mol Ther	31839484
Ting Li	METTL3 facilitates tumor progression via an mA-IGF2BP2-dependent mechanism in colorectal carcinoma.	Mol Cancer	31230592
Yujiro Nishizawa	Oncogene c-Myc promotes epitranscriptome mA reader YTHDF1 expression in colorectal cancer.	Oncotarget	29484125
Yang Bai	YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma.	Front Oncol	31131257
Yingmin Wu	mA-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1.	Mol Cancer	30979372
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Sae-Won Han	RNA editing in RHOQ promotes invasion potential in colorectal cancer.	J Exp Med	24663214
Maik Grohmann	Alternative splicing and extensive RNA editing of human TPH2 transcripts.	PLoS One	20126463
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Daphna Nachmani	Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita.	Nat Genet	31570891
Jun Liu	mA mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.	Nat Cell Biol	30154548
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Tim Hon Man Chan	A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma.	Gut	23766440
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Jun Zhang	ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1.	J Physiol Biochem	31290116
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Jin-Zhao Ma	METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N -methyladenosine-dependent primary MicroRNA processing.	Hepatology	27774652
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Huiwen Song	METTL3 and ALKBH5 oppositely regulate mA modification of mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes.	Autophagy	30870073
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Yunshu Wu	Mettl3-mediated mA RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.	Nat Commun	30429466
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Woo HH	Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability inbreast and ovarian cancer cells.	Biochim Biophys Acta Gene Regul Mech	30342176
Kosuke Taketo	The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells.	Int J Oncol	29345285
Jixiang Chen	YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells.	Cell Cycle	29135329
Daniele Fanale	Germline copy number variation in the YTHDC2 gene: does it have a role in finding a novel potential molecular target involved in pancreatic adenocarcinoma susceptibility?	Expert Opin Ther Targets	24834797
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Bo Tang	mA demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling.	Mol Cancer	31906946
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Chenyue Ding	Increased N6-methyladenosine causes infertility is associated with FTO expression.	J Cell Physiol	29384212
Jiangfeng Li	Downregulation of N-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N-methyladenosine levels.	Oncotarget	29423080
Jiarong Cai	RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway.	Onco Targets Ther	31806999
Richard T O'Neil	Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disorders.	Neurobiol Dis	21914481
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Dongkui Gong	The mA-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway.	J Exp Clin Cancer Res	31159832
Changshui Zhuang	N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis.	J Cell Mol Med	30648791
Jingyuan Tang	Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability.	J Exp Clin Cancer Res	29482572
Ahmadreza Niavarani	APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.	PLoS One	25807502
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Alessandro Barbon	Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors.	J Neurochem	20456005
Svenja Kankowski	A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy.	Front Mol Neurosci	29375302
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Dario F De Jesus	mA mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes.	Nat Metab	31867565
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Shinichiro Akichika	Cap-specific terminal -methylation of RNA by an RNA polymerase II-associated methyltransferase.	Science	30467178
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Martin Müller	Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast.	RNA Biol	30646830
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Alena Stsiapanava	Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance.	Sci Rep	31601908
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Christopher A Powell	TRMT2B is responsible for both tRNA and rRNA mU-methylation in human mitochondria.	RNA Biol	31948311
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Jahangir Alam	Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae.	Acta Crystallogr D Struct Biol	34076597
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Lindsey Van Haute	METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.	Nucleic Acids Res	31665743
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