General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000686729
Gene ID:	ENSG00000120699
Gene Name:	EXOSC8
Sequence (UNICHARACTER ENCODING)	GCЖGACGCGCGGGCGGGAAGAUGGCGGCUGGGUUCAAAACCGUGGAACCUCUGGAGUAUUACAGGAGAUUUCUGAAAGAGAACUGCCGUCCUGAUGGAAGAGAACUUGGUGAAUUCAGAЖCCACAACUGUCAACAUCGGUUCAAUUAGUACCGCAGAUGGUUCUGCUPUAGUGAAGUUGGGAAAUACUACAGUAAUCUGUGGAGUUAAAGCAGAAUUUGCAGCACCAUCAACAGAUGCCCCUGAUAAAGGAUACGUUGUUCCUAAUGUGGʍUCUACCACCCCUGUGUUCAUCGAGAUUCCGGUCUGGACCUCCUGGAGAAGAGGCCCAAGUGGCUAGCCAGUUCAUUGCAGAUGUCAUUGAAAAUUCACAGAUAAUUCAGAAAGAGGACUUAUGCAUUUCUCCAGGAAAGCUUGUCUGGGUUCUAUACUGUGAUCUCAUUUGCCUCGACUACGAUGGAAACAUUUUGGAUGCCUGCACAUUUGCUUUGCUA#CGGCUPUAAAAAAUGUACAGUUGCCUGAAGUUACUAUAAAUGAAGAAACUGCUPUAGCAGAAGUUAAUUUAAAGAAGAAAAGUUAUUUGAAUAUUAGAACUCAPCCAGUUGCAACUUCCUUUGCUGUGUUUGAUGACACUUUGCUUAUAGUUGACCCUACUGGAGAGGAGGAACAUCUGGCAACAGGAACCUUAACAAUAGUAAUGGAUGAGGAAGGCAAACUCUGUUGUCUUCACAAACCAGGCAUGUUCCCGCCACUUCAGUCCUAAACAUAUGUAGAUGAAAACUCAGUGUGAGCCUUAAAUUAGGGAGGGCCAAAUAGAAUAUGGGAUAUUUUAUUUACCUAAUUUUAGUAUAGUUUCUUAGCUACCUAAAAUGUUCUUCCAUCUUAAUGGUAUAUGUCAGUGGUUCUUAAACUUAAGACAUACAUUAGAAUCACUUGGAGGUCUUGUGAAACUAACUUGUAGAUCUUGAGACUGUACCCUGAUUUACAUUAUCCAAUUUUUUUGUUUUAUAAUUUGACAUGACAUUAAUGUUUUUUGAAAAGGAAUGAUAACUGAGAUUAAAAGUAUUGGCAAAAUAAUUUUUCAGGUGGAAGUGGGCUAACUGGAGCUAAЖCUUCAGGACUGUAUGAGCCGAGCAGUUACAAGACACAAAGAAGUUAAAAAACUGAUGGAUGAAGUAAUUAAGAGUAUGAAACCCAAAUAAЖCAGCCACCACAUUUUCAAAACAGAUUUGUAAAAAUUGUAUUUGUUAЖCACUGUGCACAAACGUUUUAUACUAAAUAAAUAUCAAACUACAUUCUUCUGAAAGAUGUUUCUAUUAUUUCUUAGGUCACUUCCAUAUAUAUUAUGUAUAGUGAAACCAUUUUUAAAAAGCAAUGACUUAGGCAAACCAACCCUAGUUUGUUAAACCAUUUCCCUGUUUUUAUUUAAAAAUGAUAAGGUUGUGCUUCU
Sequence (SHORT NAMES ENCODING)	GCm6AGACGCGCGGGCGGGAAGAUGGCGGCUGGGUUCAAAACCGUGGAACCUCUGGAGUAUUACAGGAGAUUUCUGAAAGAGAACUGCCGUCCUGAUGGAAGAGAACUUGGUGAAUUCAGAm6ACCACAACUGUCAACAUCGGUUCAAUUAGUACCGCAGAUGGUUCUGCUYUAGUGAAGUUGGGAAAUACUACAGUAAUCUGUGGAGUUAAAGCAGAAUUUGCAGCACCAUCAACAGAUGCCCCUGAUAAAGGAUACGUUGUUCCUAAUGUGGAmUCUACCACCCCUGUGUUCAUCGAGAUUCCGGUCUGGACCUCCUGGAGAAGAGGCCCAAGUGGCUAGCCAGUUCAUUGCAGAUGUCAUUGAAAAUUCACAGAUAAUUCAGAAAGAGGACUUAUGCAUUUCUCCAGGAAAGCUUGUCUGGGUUCUAUACUGUGAUCUCAUUUGCCUCGACUACGAUGGAAACAUUUUGGAUGCCUGCACAUUUGCUUUGCUAGmCGGCUYUAAAAAAUGUACAGUUGCCUGAAGUUACUAUAAAUGAAGAAACUGCUYUAGCAGAAGUUAAUUUAAAGAAGAAAAGUUAUUUGAAUAUUAGAACUCAYCCAGUUGCAACUUCCUUUGCUGUGUUUGAUGACACUUUGCUUAUAGUUGACCCUACUGGAGAGGAGGAACAUCUGGCAACAGGAACCUUAACAAUAGUAAUGGAUGAGGAAGGCAAACUCUGUUGUCUUCACAAACCAGGCAUGUUCCCGCCACUUCAGUCCUAAACAUAUGUAGAUGAAAACUCAGUGUGAGCCUUAAAUUAGGGAGGGCCAAAUAGAAUAUGGGAUAUUUUAUUUACCUAAUUUUAGUAUAGUUUCUUAGCUACCUAAAAUGUUCUUCCAUCUUAAUGGUAUAUGUCAGUGGUUCUUAAACUUAAGACAUACAUUAGAAUCACUUGGAGGUCUUGUGAAACUAACUUGUAGAUCUUGAGACUGUACCCUGAUUUACAUUAUCCAAUUUUUUUGUUUUAUAAUUUGACAUGACAUUAAUGUUUUUUGAAAAGGAAUGAUAACUGAGAUUAAAAGUAUUGGCAAAAUAAUUUUUCAGGUGGAAGUGGGCUAACUGGAGCUAAm6ACUUCAGGACUGUAUGAGCCGAGCAGUUACAAGACACAAAGAAGUUAAAAAACUGAUGGAUGAAGUAAUUAAGAGUAUGAAACCCAAAUAAm6ACAGCCACCACAUUUUCAAAACAGAUUUGUAAAAAUUGUAUUUGUUAm6ACACUGUGCACAAACGUUUUAUACUAAAUAAAUAUCAAACUACAUUCUUCUGAAAGAUGUUUCUAUUAUUUCUUAGGUCACUUCCAUAUAUAUUAUGUAUAGUGAAACCAUUUUUAAAAAGCAAUGACUUAGGCAAACCAACCCUAGUUUGUUAAACCAUUUCCCUGUUUUUAUUUAAAAAUGAUAAGGUUGUGCUUCU
Sequence (MODOMICS CODE ENCODING)	GC2000000006AGACGCGCGGGCGGGAAGAUGGCGGCUGGGUUCAAAACCGUGGAACCUCUGGAGUAUUACAGGAGAUUUCUGAAAGAGAACUGCCGUCCUGAUGGAAGAGAACUUGGUGAAUUCAGA2000000006ACCACAACUGUCAACAUCGGUUCAAUUAGUACCGCAGAUGGUUCUGCU2000000009UUAGUGAAGUUGGGAAAUACUACAGUAAUCUGUGGAGUUAAAGCAGAAUUUGCAGCACCAUCAACAGAUGCCCCUGAUAAAGGAUACGUUGUUCCUAAUGUGG2000000090AUCUACCACCCCUGUGUUCAUCGAGAUUCCGGUCUGGACCUCCUGGAGAAGAGGCCCAAGUGGCUAGCCAGUUCAUUGCAGAUGUCAUUGAAAAUUCACAGAUAAUUCAGAAAGAGGACUUAUGCAUUUCUCCAGGAAAGCUUGUCUGGGUUCUAUACUGUGAUCUCAUUUGCCUCGACUACGAUGGAAACAUUUUGGAUGCCUGCACAUUUGCUUUGCUA2000000090GCGGCU2000000009UUAAAAAAUGUACAGUUGCCUGAAGUUACUAUAAAUGAAGAAACUGCU2000000009UUAGCAGAAGUUAAUUUAAAGAAGAAAAGUUAUUUGAAUAUUAGAACUCA2000000009UCCAGUUGCAACUUCCUUUGCUGUGUUUGAUGACACUUUGCUUAUAGUUGACCCUACUGGAGAGGAGGAACAUCUGGCAACAGGAACCUUAACAAUAGUAAUGGAUGAGGAAGGCAAACUCUGUUGUCUUCACAAACCAGGCAUGUUCCCGCCACUUCAGUCCUAAACAUAUGUAGAUGAAAACUCAGUGUGAGCCUUAAAUUAGGGAGGGCCAAAUAGAAUAUGGGAUAUUUUAUUUACCUAAUUUUAGUAUAGUUUCUUAGCUACCUAAAAUGUUCUUCCAUCUUAAUGGUAUAUGUCAGUGGUUCUUAAACUUAAGACAUACAUUAGAAUCACUUGGAGGUCUUGUGAAACUAACUUGUAGAUCUUGAGACUGUACCCUGAUUUACAUUAUCCAAUUUUUUUGUUUUAUAAUUUGACAUGACAUUAAUGUUUUUUGAAAAGGAAUGAUAACUGAGAUUAAAAGUAUUGGCAAAAUAAUUUUUCAGGUGGAAGUGGGCUAACUGGAGCUAA2000000006ACUUCAGGACUGUAUGAGCCGAGCAGUUACAAGACACAAAGAAGUUAAAAAACUGAUGGAUGAAGUAAUUAAGAGUAUGAAACCCAAAUAA2000000006ACAGCCACCACAUUUUCAAAACAGAUUUGUAAAAAUUGUAUUUGUUA2000000006ACACUGUGCACAAACGUUUUAUACUAAAUAAAUAUCAAACUACAUUCUUCUGAAAGAUGUUUCUAUUAUUUCUUAGGUCACUUCCAUAUAUAUUAUGUAUAGUGAAACCAUUUUUAAAAAGCAAUGACUUAGGCAAACCAACCCUAGUUUGUUAAACCAUUUCCCUGUUUUUAUUUAAAAAUGAUAAGGUUGUGCUUCU

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	3	120	168	271	492	498	546	596	1109	1200	1247
Modification Positions	m6A	m6A	Y	Am	Gm	Y	Y	Y	m6A	m6A	m6A
Genomic Coordinates	13:37000788:+	13:37002533:+	13:37002963:+	13:37005932:+	13:37007056:+	13:37007062:+	13:37008095:+	13:37008145:+	13:37009209:+	13:37009300:+	13:37009347:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	6UuHp6YApVKv jNkxUQNx8GRd msuJfBpJvM5H VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	jaSvBXBkn3xs YkSG92k4EHDM	jaSvBXBkn3xs YkSG92k4EHDM	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	834aFpha8RvT JASnTTw2HeNE ZuM5xpZmNuDL BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8