General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000646224
Gene ID:	ENSG00000157540
Gene Name:	DYRK1A
Sequence (UNICHARACTER ENCODING)	AGCAGUUACUUUUUGCAUUCAUUUAGUGGCACCUGCUUAACCAGGAGAUUAAAAGCCAUCCACAGACCAUGAUUGUGAGUGCAUUUGAAACGCCACUUUAUGUUUCGAAACCAUCUCUGUUUAGUUUUUGAAAUGCUGUCCUACAACCUCUAUGACUUGCUGAGAAACACCAAUUUCCGAGGGGUCUCUUUGAACCUAACACGAAAGUUUGCGCAACAGAUGUGCACUGCACUGCUUUUCCUUGCGACUCCAGAACUUAGUAUCAUUCACUGUGAUCUAAAACCUGAAAAUAUCCUUCUUUGUAACCCCAAACGCAGUGCAAUCAAGAUAGUUGACUUUGGCAGUUCUUGUCAGUUGGGGCAGAGGAUAUACCAGUAUAUUCAGAGUCGCUUUUAUCGGUCUCCAGAGGUGCUACUGGGAAUGCCUUAUGACCUUGCCAUUGAUAUGUGGUCCCUCGGGUGUAUUUUGGUUGAAAUGCACACUGGAGAACCUCUGUUCAGUGGUGCCAAUGAGGUAGAUCAGAUGAAUAAAAUAGUGGAAGUUCUGGGUAUUCCACCUGCUCAUAUUCUUGACCAAGCACCAAAAGCAAGAAAGUUCUUUGAGAAGUUGCCAGAUGGCACUUGGAACUUAAAGAAGACCAAAGAUGGAAAACGGGAGUACAAACCACCAGGAACCCGUAAACUUCAUAACAUUCUUGGAGUGGAAACAGGAGGACCUGGUGGGCGACGUGCUGGGGAGUCAGGUCAUACGGUCGCUGACUACUUGAAGUUCAAAGACCUCAUUUUAAGGAUGCUUGAUUAUGACCCCAAAACUCGAAUUCAACCUUAUUAUGCUCUGCAGCACAGUUUCUUCAAGAAAACAGCUGAUGAAGGUACAAAUACAAGUAAUAGUGUAUCUACAAGCCCCGCCAUGGAGCAGUCUCAGUCUUCGGGCACCACCUCCAGUACAUCGUCAAGCUCAGGUGGCUCAUCGGGGACAAGCAACAGUGGGAGAGCCCGGUCGGAUCCGACGCACCAGCAUCGGCACAGUGGUGGGCACUUCACAGCUGCCGUGCAGGCCAUGGACUGCGAGACACACAGUCCCCAGGUGCGUCAGCAAUUUCCUGCUCCUCUUGGUUGGUCAGGCACUGAAGCUCCUACACAGGUCACUGUUGAAACUCAUCCUGUUCAAGAAACAACCUUUCAUGUAGCCCCUCAACAGAAUGCAUUGCAUCAUCACCAUGGUAACAGUUCCCAUCACCAUCACCACCACCACCACCAUCACCACCACCAUGGЖCAACAAGCCUUGGGUAACCGGACCAGGCCAAGGGUCUACAAUUCUCCAACGAAUAGCUCCUCUACCCAAGAUUCUAUGGAGGUUGGCCACAGUCACCACUCCAUGACAUCCCUGUCUUCCUCAACGACUUCUUCCUCGACAUCUUCCUCCUCUACUGGUAACCAAGGCAAUCAGGCCUACCAGAAUCGCCCAGUGGCUGCUAAUACCUUGGЖCUUUGGЖCAGAAUGGAGCUAUGGЖCGUUAAUUUGACCGUCUACUCCAAUCCCCGCCAAGAGЖCUGGCAUAGCUGGЖCAUCCAACAUACCAAUUUUCUGCUAAUACAGGUCCUGCACAUUACAUGЖCUGAAGGЖCAUCUGACAAUGAGGCAAGGGGCUGAUAGAGAAGAGUCCCCCAUGACAGGAGUUUGUGUGCAACAGAGUCCUGUAGCUAGCUCGUGACUACAUUGAAACUUGAGUUUGUUUCUUG
Sequence (SHORT NAMES ENCODING)	AGCAGUUACUUUUUGCAUUCAUUUAGUGGCACCUGCUUAACCAGGAGAUUAAAAGCCAUCCACAGACCAUGAUUGUGAGUGCAUUUGAAACGCCACUUUAUGUUUCGAAACCAUCUCUGUUUAGUUUUUGAAAUGCUGUCCUACAACCUCUAUGACUUGCUGAGAAACACCAAUUUCCGAGGGGUCUCUUUGAACCUAACACGAAAGUUUGCGCAACAGAUGUGCACUGCACUGCUUUUCCUUGCGACUCCAGAACUUAGUAUCAUUCACUGUGAUCUAAAACCUGAAAAUAUCCUUCUUUGUAACCCCAAACGCAGUGCAAUCAAGAUAGUUGACUUUGGCAGUUCUUGUCAGUUGGGGCAGAGGAUAUACCAGUAUAUUCAGAGUCGCUUUUAUCGGUCUCCAGAGGUGCUACUGGGAAUGCCUUAUGACCUUGCCAUUGAUAUGUGGUCCCUCGGGUGUAUUUUGGUUGAAAUGCACACUGGAGAACCUCUGUUCAGUGGUGCCAAUGAGGUAGAUCAGAUGAAUAAAAUAGUGGAAGUUCUGGGUAUUCCACCUGCUCAUAUUCUUGACCAAGCACCAAAAGCAAGAAAGUUCUUUGAGAAGUUGCCAGAUGGCACUUGGAACUUAAAGAAGACCAAAGAUGGAAAACGGGAGUACAAACCACCAGGAACCCGUAAACUUCAUAACAUUCUUGGAGUGGAAACAGGAGGACCUGGUGGGCGACGUGCUGGGGAGUCAGGUCAUACGGUCGCUGACUACUUGAAGUUCAAAGACCUCAUUUUAAGGAUGCUUGAUUAUGACCCCAAAACUCGAAUUCAACCUUAUUAUGCUCUGCAGCACAGUUUCUUCAAGAAAACAGCUGAUGAAGGUACAAAUACAAGUAAUAGUGUAUCUACAAGCCCCGCCAUGGAGCAGUCUCAGUCUUCGGGCACCACCUCCAGUACAUCGUCAAGCUCAGGUGGCUCAUCGGGGACAAGCAACAGUGGGAGAGCCCGGUCGGAUCCGACGCACCAGCAUCGGCACAGUGGUGGGCACUUCACAGCUGCCGUGCAGGCCAUGGACUGCGAGACACACAGUCCCCAGGUGCGUCAGCAAUUUCCUGCUCCUCUUGGUUGGUCAGGCACUGAAGCUCCUACACAGGUCACUGUUGAAACUCAUCCUGUUCAAGAAACAACCUUUCAUGUAGCCCCUCAACAGAAUGCAUUGCAUCAUCACCAUGGUAACAGUUCCCAUCACCAUCACCACCACCACCACCAUCACCACCACCAUGGm6ACAACAAGCCUUGGGUAACCGGACCAGGCCAAGGGUCUACAAUUCUCCAACGAAUAGCUCCUCUACCCAAGAUUCUAUGGAGGUUGGCCACAGUCACCACUCCAUGACAUCCCUGUCUUCCUCAACGACUUCUUCCUCGACAUCUUCCUCCUCUACUGGUAACCAAGGCAAUCAGGCCUACCAGAAUCGCCCAGUGGCUGCUAAUACCUUGGm6ACUUUGGm6ACAGAAUGGAGCUAUGGm6ACGUUAAUUUGACCGUCUACUCCAAUCCCCGCCAAGAGm6ACUGGCAUAGCUGGm6ACAUCCAACAUACCAAUUUUCUGCUAAUACAGGUCCUGCACAUUACAUGm6ACUGAAGGm6ACAUCUGACAAUGAGGCAAGGGGCUGAUAGAGAAGAGUCCCCCAUGACAGGAGUUUGUGUGCAACAGAGUCCUGUAGCUAGCUCGUGACUACAUUGAAACUUGAGUUUGUUUCUUG
Sequence (MODOMICS CODE ENCODING)	AGCAGUUACUUUUUGCAUUCAUUUAGUGGCACCUGCUUAACCAGGAGAUUAAAAGCCAUCCACAGACCAUGAUUGUGAGUGCAUUUGAAACGCCACUUUAUGUUUCGAAACCAUCUCUGUUUAGUUUUUGAAAUGCUGUCCUACAACCUCUAUGACUUGCUGAGAAACACCAAUUUCCGAGGGGUCUCUUUGAACCUAACACGAAAGUUUGCGCAACAGAUGUGCACUGCACUGCUUUUCCUUGCGACUCCAGAACUUAGUAUCAUUCACUGUGAUCUAAAACCUGAAAAUAUCCUUCUUUGUAACCCCAAACGCAGUGCAAUCAAGAUAGUUGACUUUGGCAGUUCUUGUCAGUUGGGGCAGAGGAUAUACCAGUAUAUUCAGAGUCGCUUUUAUCGGUCUCCAGAGGUGCUACUGGGAAUGCCUUAUGACCUUGCCAUUGAUAUGUGGUCCCUCGGGUGUAUUUUGGUUGAAAUGCACACUGGAGAACCUCUGUUCAGUGGUGCCAAUGAGGUAGAUCAGAUGAAUAAAAUAGUGGAAGUUCUGGGUAUUCCACCUGCUCAUAUUCUUGACCAAGCACCAAAAGCAAGAAAGUUCUUUGAGAAGUUGCCAGAUGGCACUUGGAACUUAAAGAAGACCAAAGAUGGAAAACGGGAGUACAAACCACCAGGAACCCGUAAACUUCAUAACAUUCUUGGAGUGGAAACAGGAGGACCUGGUGGGCGACGUGCUGGGGAGUCAGGUCAUACGGUCGCUGACUACUUGAAGUUCAAAGACCUCAUUUUAAGGAUGCUUGAUUAUGACCCCAAAACUCGAAUUCAACCUUAUUAUGCUCUGCAGCACAGUUUCUUCAAGAAAACAGCUGAUGAAGGUACAAAUACAAGUAAUAGUGUAUCUACAAGCCCCGCCAUGGAGCAGUCUCAGUCUUCGGGCACCACCUCCAGUACAUCGUCAAGCUCAGGUGGCUCAUCGGGGACAAGCAACAGUGGGAGAGCCCGGUCGGAUCCGACGCACCAGCAUCGGCACAGUGGUGGGCACUUCACAGCUGCCGUGCAGGCCAUGGACUGCGAGACACACAGUCCCCAGGUGCGUCAGCAAUUUCCUGCUCCUCUUGGUUGGUCAGGCACUGAAGCUCCUACACAGGUCACUGUUGAAACUCAUCCUGUUCAAGAAACAACCUUUCAUGUAGCCCCUCAACAGAAUGCAUUGCAUCAUCACCAUGGUAACAGUUCCCAUCACCAUCACCACCACCACCACCAUCACCACCACCAUGG2000000006ACAACAAGCCUUGGGUAACCGGACCAGGCCAAGGGUCUACAAUUCUCCAACGAAUAGCUCCUCUACCCAAGAUUCUAUGGAGGUUGGCCACAGUCACCACUCCAUGACAUCCCUGUCUUCCUCAACGACUUCUUCCUCGACAUCUUCCUCCUCUACUGGUAACCAAGGCAAUCAGGCCUACCAGAAUCGCCCAGUGGCUGCUAAUACCUUGG2000000006ACUUUGG2000000006ACAGAAUGGAGCUAUGG2000000006ACGUUAAUUUGACCGUCUACUCCAAUCCCCGCCAAGAG2000000006ACUGGCAUAGCUGG2000000006ACAUCCAACAUACCAAUUUUCUGCUAAUACAGGUCCUGCACAUUACAUG2000000006ACUGAAGG2000000006ACAUCUGACAAUGAGGCAAGGGGCUGAUAGAGAAGAGUCCCCCAUGACAGGAGUUUGUGUGCAACAGAGUCCUGUAGCUAGCUCGUGACUACAUUGAAACUUGAGUUUGUUUCUUG

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	1275	1487	1494	1511	1549	1563	1612	1620
Modification Positions	m6A	m6A	m6A	m6A	m6A	m6A	m6A	m6A
Genomic Coordinates	21:37512099:+	21:37512311:+	21:37512318:+	21:37512335:+	21:37512373:+	21:37512387:+	21:37512436:+	21:37512444:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	3TeAZFYFxgvp 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U D6ncpa2PPWj3	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U KENzb7mwdBd9 KjeH7Nsffuas PF5iqBNSbHaa UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn KENzb7mwdBd9 KjeH7Nsffuas UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn aJksAshEgQ8U KENzb7mwdBd9 KjeH7Nsffuas PF5iqBNSbHaa UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BkoLW2CBToyL KENzb7mwdBd9 Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn KENzb7mwdBd9 KjeH7Nsffuas Lny8GcCeVGc9 PF5iqBNSbHaa UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 6AyXsheySjfx 6UuHp6YApVKv Ap2q43bQLNek jNkxUQNx8GRd msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BkoLW2CBToyL UKen6WEino9G	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb Ap2q43bQLNek gBgcfFQ5WN9C jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn UKen6WEino9G