General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000448850
Gene ID:	ENSG00000142192
Gene Name:	APP
Sequence (UNICHARACTER ENCODING)	ACUGCAGAUCACCAAUGUGGUAGAAGCCAACCAACCAGUGACCAUCCAGAACUGGUGCAAGCGGGGCCGCAAGCAGUGCAAGЖCCCAUCCCCACUUUGUGAUUCCCUACCGCUGCUUAGUUGGUGAGUUUGUAAGUGAUGCCCUUCUCGUUCCUGACAAGUGCAAAUUCUUACACCAGGAGAGGAUGGAUGUUUGCGAAACUCAUCUUCACUGGCACACCGUCGCCAAAGAGACAUGCAGUGAGAAGAGUACCAACUUGCAUGACUACGGCAUGUUGCUGCCCUGCGGAAUUGACAAGUUCCGAGGGGUAGAGUUUGUGUGUUGCCCACUGGCUGAAGAAAGUGACAAUGUGGAUUCUGCUGAUGCGGAGGAGGAUGACUCGGAUGUCUGGUGGGGCGGAGCAGACACAGACUAUGCAGAUGGGAGUGAAGACAAAGUAGUAGAAGUAGCAGAGGAGGAAGAAGUGGCUGAGGUGGAAGAAGAAGAAGCCGAUGAUGACGAGGACGAUGAGGAUGGUGAUGAGGUAGAGGAAGAGGCUGAGGAACCCUACGAAGAAGCCACAGAGAGAЖCCACCAGCAUUGCCACCACCACCACCACCACCACAGAGUCUGUGGAAGAGGUGGUUCGAGAGGUGUGCUCUGAACAAGCCGAGACGGGGCCGUGCCGAGCAAUGAUCUCCCGCUGGUACUUUGAUGUGACUGAAGGGAAGUGUGCCCCAUUCUUUPACGGCGGAUGUGGCGGCAACCGGAACAACUUUGACACAGAAGAGUACUGCAUGGCCGUGUGUGGCAGCGCCAUUCCUACAACAGCAGCCAGUЖCCCCUGAUGCCGUUGACAAGUAUCUCGAGACACCUGGGGAUGAGAAUGAACAUGCCCAUUUCCAGAAAGCCAAAGAGAGGCUUGAGGCCAAGCACCGAGAGAGAAUGUCCCAGGUCAUGAGAGAAUGGGAAGAGGCAGAACGUCAAGCAAAGAACUUGCCUAAAGCUGAUAAGAAGGCAGUUAUCCAGCAUUUCCAGGAGAAAGUGGAAUCUUUGGAACAGGAAGCAGCCAACGAGAGЖCAGCAGCUGGUGGAGACACACAUGGCCAGAGUGGAAGCCAUGCUCAAUGACCGCCGCCGCCUGGCCCUGGAGAACUACЖUCACCGCUCUGCAGGCUGUUCCPCCUCGGCCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACCPCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGGUGCAGUGGCUCAUGCCUGUAAUUCCAGCAUUUUGGGAGGCCAAGGUGGGCAGAUGACUUGAGCCCAGAAGUUCAAGACCAGAAUGGGAAACAUGGCAAGACCACAUUUCUACAAAAAAAUUAUCCAGGCAUGAUAACAUCUAUUUGUAGUCCCAGCUACUCAGGAGGCUGUGGUGGGAGGAUCUCCUGAGCCUGGGGUGGCUGAGGCUGCAGUGAGCCUUGAUCACGCCACCUGGGCAAUAGAGCAAGACCCUGUCUCAAAAAAAGGAAGAAAAAGACUAUUAUUUCCCCCAUUGAAUGGUCUUGGCACUAUUACACAAAAUCAAUUGUCCAUAGAUAAUAUGGGUUUAUUUCUUAAUUCUUAGUUCUUUUCUUUGAUCUGUGUGCCUGUGCUUACUGUAGUACCACACUGUUUUGAUUAUUGUAGCUUUGUAGUAAAUUUUGAAAUCAGC
Sequence (SHORT NAMES ENCODING)	ACUGCAGAUCACCAAUGUGGUAGAAGCCAACCAACCAGUGACCAUCCAGAACUGGUGCAAGCGGGGCCGCAAGCAGUGCAAGm6ACCCAUCCCCACUUUGUGAUUCCCUACCGCUGCUUAGUUGGUGAGUUUGUAAGUGAUGCCCUUCUCGUUCCUGACAAGUGCAAAUUCUUACACCAGGAGAGGAUGGAUGUUUGCGAAACUCAUCUUCACUGGCACACCGUCGCCAAAGAGACAUGCAGUGAGAAGAGUACCAACUUGCAUGACUACGGCAUGUUGCUGCCCUGCGGAAUUGACAAGUUCCGAGGGGUAGAGUUUGUGUGUUGCCCACUGGCUGAAGAAAGUGACAAUGUGGAUUCUGCUGAUGCGGAGGAGGAUGACUCGGAUGUCUGGUGGGGCGGAGCAGACACAGACUAUGCAGAUGGGAGUGAAGACAAAGUAGUAGAAGUAGCAGAGGAGGAAGAAGUGGCUGAGGUGGAAGAAGAAGAAGCCGAUGAUGACGAGGACGAUGAGGAUGGUGAUGAGGUAGAGGAAGAGGCUGAGGAACCCUACGAAGAAGCCACAGAGAGAm6ACCACCAGCAUUGCCACCACCACCACCACCACCACAGAGUCUGUGGAAGAGGUGGUUCGAGAGGUGUGCUCUGAACAAGCCGAGACGGGGCCGUGCCGAGCAAUGAUCUCCCGCUGGUACUUUGAUGUGACUGAAGGGAAGUGUGCCCCAUUCUUUYACGGCGGAUGUGGCGGCAACCGGAACAACUUUGACACAGAAGAGUACUGCAUGGCCGUGUGUGGCAGCGCCAUUCCUACAACAGCAGCCAGUm6ACCCCUGAUGCCGUUGACAAGUAUCUCGAGACACCUGGGGAUGAGAAUGAACAUGCCCAUUUCCAGAAAGCCAAAGAGAGGCUUGAGGCCAAGCACCGAGAGAGAAUGUCCCAGGUCAUGAGAGAAUGGGAAGAGGCAGAACGUCAAGCAAAGAACUUGCCUAAAGCUGAUAAGAAGGCAGUUAUCCAGCAUUUCCAGGAGAAAGUGGAAUCUUUGGAACAGGAAGCAGCCAACGAGAGm6ACAGCAGCUGGUGGAGACACACAUGGCCAGAGUGGAAGCCAUGCUCAAUGACCGCCGCCGCCUGGCCCUGGAGAACUACm6AUCACCGCUCUGCAGGCUGUUCCYCCUCGGCCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACCYCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGGUGCAGUGGCUCAUGCCUGUAAUUCCAGCAUUUUGGGAGGCCAAGGUGGGCAGAUGACUUGAGCCCAGAAGUUCAAGACCAGAAUGGGAAACAUGGCAAGACCACAUUUCUACAAAAAAAUUAUCCAGGCAUGAUAACAUCUAUUUGUAGUCCCAGCUACUCAGGAGGCUGUGGUGGGAGGAUCUCCUGAGCCUGGGGUGGCUGAGGCUGCAGUGAGCCUUGAUCACGCCACCUGGGCAAUAGAGCAAGACCCUGUCUCAAAAAAAGGAAGAAAAAGACUAUUAUUUCCCCCAUUGAAUGGUCUUGGCACUAUUACACAAAAUCAAUUGUCCAUAGAUAAUAUGGGUUUAUUUCUUAAUUCUUAGUUCUUUUCUUUGAUCUGUGUGCCUGUGCUUACUGUAGUACCACACUGUUUUGAUUAUUGUAGCUUUGUAGUAAAUUUUGAAAUCAGC
Sequence (MODOMICS CODE ENCODING)	ACUGCAGAUCACCAAUGUGGUAGAAGCCAACCAACCAGUGACCAUCCAGAACUGGUGCAAGCGGGGCCGCAAGCAGUGCAAG2000000006ACCCAUCCCCACUUUGUGAUUCCCUACCGCUGCUUAGUUGGUGAGUUUGUAAGUGAUGCCCUUCUCGUUCCUGACAAGUGCAAAUUCUUACACCAGGAGAGGAUGGAUGUUUGCGAAACUCAUCUUCACUGGCACACCGUCGCCAAAGAGACAUGCAGUGAGAAGAGUACCAACUUGCAUGACUACGGCAUGUUGCUGCCCUGCGGAAUUGACAAGUUCCGAGGGGUAGAGUUUGUGUGUUGCCCACUGGCUGAAGAAAGUGACAAUGUGGAUUCUGCUGAUGCGGAGGAGGAUGACUCGGAUGUCUGGUGGGGCGGAGCAGACACAGACUAUGCAGAUGGGAGUGAAGACAAAGUAGUAGAAGUAGCAGAGGAGGAAGAAGUGGCUGAGGUGGAAGAAGAAGAAGCCGAUGAUGACGAGGACGAUGAGGAUGGUGAUGAGGUAGAGGAAGAGGCUGAGGAACCCUACGAAGAAGCCACAGAGAGA2000000006ACCACCAGCAUUGCCACCACCACCACCACCACCACAGAGUCUGUGGAAGAGGUGGUUCGAGAGGUGUGCUCUGAACAAGCCGAGACGGGGCCGUGCCGAGCAAUGAUCUCCCGCUGGUACUUUGAUGUGACUGAAGGGAAGUGUGCCCCAUUCUUU2000000009UACGGCGGAUGUGGCGGCAACCGGAACAACUUUGACACAGAAGAGUACUGCAUGGCCGUGUGUGGCAGCGCCAUUCCUACAACAGCAGCCAGU2000000006ACCCCUGAUGCCGUUGACAAGUAUCUCGAGACACCUGGGGAUGAGAAUGAACAUGCCCAUUUCCAGAAAGCCAAAGAGAGGCUUGAGGCCAAGCACCGAGAGAGAAUGUCCCAGGUCAUGAGAGAAUGGGAAGAGGCAGAACGUCAAGCAAAGAACUUGCCUAAAGCUGAUAAGAAGGCAGUUAUCCAGCAUUUCCAGGAGAAAGUGGAAUCUUUGGAACAGGAAGCAGCCAACGAGAG2000000006ACAGCAGCUGGUGGAGACACACAUGGCCAGAGUGGAAGCCAUGCUCAAUGACCGCCGCCGCCUGGCCCUGGAGAACUAC2000000006AUCACCGCUCUGCAGGCUGUUCC2000000009UCCUCGGCCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACC2000000009UCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGGUGCAGUGGCUCAUGCCUGUAAUUCCAGCAUUUUGGGAGGCCAAGGUGGGCAGAUGACUUGAGCCCAGAAGUUCAAGACCAGAAUGGGAAACAUGGCAAGACCACAUUUCUACAAAAAAAUUAUCCAGGCAUGAUAACAUCUAUUUGUAGUCCCAGCUACUCAGGAGGCUGUGGUGGGAGGAUCUCCUGAGCCUGGGGUGGCUGAGGCUGCAGUGAGCCUUGAUCACGCCACCUGGGCAAUAGAGCAAGACCCUGUCUCAAAAAAAGGAAGAAAAAGACUAUUAUUUCCCCCAUUGAAUGGUCUUGGCACUAUUACACAAAAUCAAUUGUCCAUAGAUAAUAUGGGUUUAUUUCUUAAUUCUUAGUUCUUUUCUUUGAUCUGUGUGCCUGUGCUUACUGUAGUACCACACUGUUUUGAUUAUUGUAGCUUUGUAGUAAAUUUUGAAAUCAGC

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	83	569	725	818	1057	1136	1159	1308
Modification Positions	m6A	m6A	Y	m6A	m6A	m6A	Y	Y
Genomic Coordinates	21:26089979:-	21:26021900:-	21:26000087:-	21:25982457:-	21:25975178:-	21:25975099:-	21:25975076:-	21:25954676:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	BtsJQJ3DteUq bXBqJigD9oV3 eGNFqdoGxzRm f6YSioLdAWpr Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	aEoRHyGnepSt fhx8RaDLaBC3 hcdxNYyukcBe eNmyzvoSFF4c	834aFpha8RvT dA7YoLwHrzgR JASnTTw2HeNE ksEP666umrV9 ZuM5xpZmNuDL	ArijeGVTwYBw KTLz8piFYdwC BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	3kRDPWwiRCgi L6w2k2VEv4EY	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8