General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000707134
Gene ID:	ENSG00000142192
Gene Name:	APP
Sequence (UNICHARACTER ENCODING)	ACACGCUUUCAGGAGAGGAGCCGUGUGAUCAUUUGCCAGAGAAGGAUAGGCUGGUGGGUGCUGAGACCAGAAUCUUUAUAGCAGAAACUUGUGAAGCGUUCCAGCUGAAAGUCCAAUCUCUAAACCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACCPCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGAUGAGCUGCUUCAGAAAGAGCAAAACUAUUCAGAUGACGUCUUGGCCAACAUGAUUAGUGAЖCCAAGGAUCAGUUACGGAAACGAUGCUCUCAUGCCAUCUUUGACCGAAACGAAAACCACCGUGGAGCUCCUUCCCGUGAAUGGAGAGUUCAGCCUGGACGAUCUCCAGCCGUGGCAUUCUUUUGGGGCUGACUCUGUGCCAGCCAACACAGAAAACGAAGUUGAGCCUGUUGAUGCCCGCCCUGCUGCCGACCGAGGACUGACCACUCGACCAGGUUCUGGGUUGACAAAUAUCAAGACGGAGGAGAUCUCUGAAGUGAAGAUGGAUGCAGAAUUCCGACAUGACUCAGGAUAUGAAGUUCAUCAUCAAAAAUUGGUGUUCUUUGCAGAAGAUGUGGGUUCAAACAAAGGUGCAAUCAUUGGACUCAUGGUGGGCGGUGUUGUCAUAGCGACAGUGAUCGUCAUCACCUUGGUGAUGCUGAAGAAGAAACAGUACЖCAPCCAUUCAUCAUGGUGUGGUGGAGGUUGACGCCGCUGUCACCCCAGAGGAGCGCCACCUGUCCAAGAUGCAGCAGAACGGCUACGAAAAUCCAACCUACAAGUUCUUUGAGCAGAUGCAGAACUAGACCCCCGCCACAGCAGCCUCUGAAGUUGGACAGCAAAACCAUUGCUUCACUACCCAUCGGUGUCCAUUUAUAGAAUAAUGUGGGAAGAAACAAACCCGUUUUAUGAUUUACUCAUUAUCGCCUUUUGACAGCUGUGCUGUAЖCACAAGUAGAUGCCUGAACUUGAAUUAAUCCACACAUCAGUAAUGUAUUCUAUCUCUCUPUACAUUUUGGUCUCUAUACUACAUUAUUAAUGGGUUUUGUGUACUGUAAAGAAUUUAGCUGUAUCAAACUAGUGCAUGAAUAGAUUCUCUCCUGAUUAUUUAUCACAUAGCCCCUUAGCCAGUUGUAUAUUAUUCUUGUGGUUUGUGACCCAAUUAAGUCCUACUPUACAUAUGCUPUAAGAAUCGAUGGGGGAUGCUUCAUGUGAACGUGGGAGUUCAGCUGCUUCUCUUGCCUAAGUAUUCCUUUCCUGAUCACUAUGCAUUUUAAAGUUAAЖCAUUUUUAAGUAUUUCAGAUGCUPUAGAGAGAUUUUUUUUCCAUGACUGCAUUUUACUGUACAGAUUGCUGCUUCUGCUAUAUUUGUGAUAUAGGAAUUAAGAGGAUACACACGUUUGUUUCUUCGUGCCUGUUUUAUGUGCACACAUUAGGCAUUGAGACUUCAAGCUUUUCUUUUUUUGUCCACGUAUCUUUGGGUCUUUGAUAAAGAAAAGAAUCCCUGUUCAUUGUAAGCACUUUUACGGGGCGGGUGGGGAGGGGUGCUCUGCUGGUCUUCAAUUACCAAGAAUUCUCCAAAACAAUUUUCUGCAGGAUGAUUGUACAGAAUCAUUGCUUAUGACAUGAUCGCUUUCUACACUGUAUUACAUAAAUAAAUUAAAUAAAAUAACCCCGGGCAAGACUUUUCUUUGЖAGGAUGACUACЖ#ACAUUAAAUAAUCGAAGUAAUUUUGGGUGGGGAGAAGAGGCAGAUUCAAUUUUCUPUAACCAGUCUGAAGUUUCAUUUAUGAUACAAAAGAAGAUGAAAAUGGAAGUGGCAAUAUAAGGGGAUGAGGAAGGCAUGCCUGGACAAACCCUUCUUUUAAGAUGUGUCUUCAAUUUGUAUAAAAUGGUGUUUUCAUGUAAAUAAAUACAUUCUU
Sequence (SHORT NAMES ENCODING)	ACACGCUUUCAGGAGAGGAGCCGUGUGAUCAUUUGCCAGAGAAGGAUAGGCUGGUGGGUGCUGAGACCAGAAUCUUUAUAGCAGAAACUUGUGAAGCGUUCCAGCUGAAAGUCCAAUCUCUAAACCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACCYCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGAUGAGCUGCUUCAGAAAGAGCAAAACUAUUCAGAUGACGUCUUGGCCAACAUGAUUAGUGAm6ACCAAGGAUCAGUUACGGAAACGAUGCUCUCAUGCCAUCUUUGACCGAAACGAAAACCACCGUGGAGCUCCUUCCCGUGAAUGGAGAGUUCAGCCUGGACGAUCUCCAGCCGUGGCAUUCUUUUGGGGCUGACUCUGUGCCAGCCAACACAGAAAACGAAGUUGAGCCUGUUGAUGCCCGCCCUGCUGCCGACCGAGGACUGACCACUCGACCAGGUUCUGGGUUGACAAAUAUCAAGACGGAGGAGAUCUCUGAAGUGAAGAUGGAUGCAGAAUUCCGACAUGACUCAGGAUAUGAAGUUCAUCAUCAAAAAUUGGUGUUCUUUGCAGAAGAUGUGGGUUCAAACAAAGGUGCAAUCAUUGGACUCAUGGUGGGCGGUGUUGUCAUAGCGACAGUGAUCGUCAUCACCUUGGUGAUGCUGAAGAAGAAACAGUACm6ACAYCCAUUCAUCAUGGUGUGGUGGAGGUUGACGCCGCUGUCACCCCAGAGGAGCGCCACCUGUCCAAGAUGCAGCAGAACGGCUACGAAAAUCCAACCUACAAGUUCUUUGAGCAGAUGCAGAACUAGACCCCCGCCACAGCAGCCUCUGAAGUUGGACAGCAAAACCAUUGCUUCACUACCCAUCGGUGUCCAUUUAUAGAAUAAUGUGGGAAGAAACAAACCCGUUUUAUGAUUUACUCAUUAUCGCCUUUUGACAGCUGUGCUGUAm6ACACAAGUAGAUGCCUGAACUUGAAUUAAUCCACACAUCAGUAAUGUAUUCUAUCUCUCUYUACAUUUUGGUCUCUAUACUACAUUAUUAAUGGGUUUUGUGUACUGUAAAGAAUUUAGCUGUAUCAAACUAGUGCAUGAAUAGAUUCUCUCCUGAUUAUUUAUCACAUAGCCCCUUAGCCAGUUGUAUAUUAUUCUUGUGGUUUGUGACCCAAUUAAGUCCUACUYUACAUAUGCUYUAAGAAUCGAUGGGGGAUGCUUCAUGUGAACGUGGGAGUUCAGCUGCUUCUCUUGCCUAAGUAUUCCUUUCCUGAUCACUAUGCAUUUUAAAGUUAAm6ACAUUUUUAAGUAUUUCAGAUGCUYUAGAGAGAUUUUUUUUCCAUGACUGCAUUUUACUGUACAGAUUGCUGCUUCUGCUAUAUUUGUGAUAUAGGAAUUAAGAGGAUACACACGUUUGUUUCUUCGUGCCUGUUUUAUGUGCACACAUUAGGCAUUGAGACUUCAAGCUUUUCUUUUUUUGUCCACGUAUCUUUGGGUCUUUGAUAAAGAAAAGAAUCCCUGUUCAUUGUAAGCACUUUUACGGGGCGGGUGGGGAGGGGUGCUCUGCUGGUCUUCAAUUACCAAGAAUUCUCCAAAACAAUUUUCUGCAGGAUGAUUGUACAGAAUCAUUGCUUAUGACAUGAUCGCUUUCUACACUGUAUUACAUAAAUAAAUUAAAUAAAAUAACCCCGGGCAAGACUUUUCUUUGm6AAGGAUGACUACm6AGmACAUUAAAUAAUCGAAGUAAUUUUGGGUGGGGAGAAGAGGCAGAUUCAAUUUUCUYUAACCAGUCUGAAGUUUCAUUUAUGAUACAAAAGAAGAUGAAAAUGGAAGUGGCAAUAUAAGGGGAUGAGGAAGGCAUGCCUGGACAAACCCUUCUUUUAAGAUGUGUCUUCAAUUUGUAUAAAAUGGUGUUUUCAUGUAAAUAAAUACAUUCUU
Sequence (MODOMICS CODE ENCODING)	ACACGCUUUCAGGAGAGGAGCCGUGUGAUCAUUUGCCAGAGAAGGAUAGGCUGGUGGGUGCUGAGACCAGAAUCUUUAUAGCAGAAACUUGUGAAGCGUUCCAGCUGAAAGUCCAAUCUCUAAACCUCGUCACGUGUUCAAUAUGCUAAAGAAGUAUGUCCGCGCAGAACAGAAGGACAGACAGCACACCCUAAAGCAUUUCGAGCAUGUGCGCAUGGUGGAUCCCAAGAAAGCCGCUCAGAUCCGGUCCCAGGUUAUGACACACC2000000009UCCGUGUGAUUUAUGAGCGCAUGAAUCAGUCUCUCUCCCUGCUCUACAACGUGCCUGCAGUGGCCGAGGAGAUUCAGGAUGAAGUUGAUGAGCUGCUUCAGAAAGAGCAAAACUAUUCAGAUGACGUCUUGGCCAACAUGAUUAGUGA2000000006ACCAAGGAUCAGUUACGGAAACGAUGCUCUCAUGCCAUCUUUGACCGAAACGAAAACCACCGUGGAGCUCCUUCCCGUGAAUGGAGAGUUCAGCCUGGACGAUCUCCAGCCGUGGCAUUCUUUUGGGGCUGACUCUGUGCCAGCCAACACAGAAAACGAAGUUGAGCCUGUUGAUGCCCGCCCUGCUGCCGACCGAGGACUGACCACUCGACCAGGUUCUGGGUUGACAAAUAUCAAGACGGAGGAGAUCUCUGAAGUGAAGAUGGAUGCAGAAUUCCGACAUGACUCAGGAUAUGAAGUUCAUCAUCAAAAAUUGGUGUUCUUUGCAGAAGAUGUGGGUUCAAACAAAGGUGCAAUCAUUGGACUCAUGGUGGGCGGUGUUGUCAUAGCGACAGUGAUCGUCAUCACCUUGGUGAUGCUGAAGAAGAAACAGUAC2000000006ACA2000000009UCCAUUCAUCAUGGUGUGGUGGAGGUUGACGCCGCUGUCACCCCAGAGGAGCGCCACCUGUCCAAGAUGCAGCAGAACGGCUACGAAAAUCCAACCUACAAGUUCUUUGAGCAGAUGCAGAACUAGACCCCCGCCACAGCAGCCUCUGAAGUUGGACAGCAAAACCAUUGCUUCACUACCCAUCGGUGUCCAUUUAUAGAAUAAUGUGGGAAGAAACAAACCCGUUUUAUGAUUUACUCAUUAUCGCCUUUUGACAGCUGUGCUGUA2000000006ACACAAGUAGAUGCCUGAACUUGAAUUAAUCCACACAUCAGUAAUGUAUUCUAUCUCUCU2000000009UUACAUUUUGGUCUCUAUACUACAUUAUUAAUGGGUUUUGUGUACUGUAAAGAAUUUAGCUGUAUCAAACUAGUGCAUGAAUAGAUUCUCUCCUGAUUAUUUAUCACAUAGCCCCUUAGCCAGUUGUAUAUUAUUCUUGUGGUUUGUGACCCAAUUAAGUCCUACU2000000009UUACAUAUGCU2000000009UUAAGAAUCGAUGGGGGAUGCUUCAUGUGAACGUGGGAGUUCAGCUGCUUCUCUUGCCUAAGUAUUCCUUUCCUGAUCACUAUGCAUUUUAAAGUUAA2000000006ACAUUUUUAAGUAUUUCAGAUGCU2000000009UUAGAGAGAUUUUUUUUCCAUGACUGCAUUUUACUGUACAGAUUGCUGCUUCUGCUAUAUUUGUGAUAUAGGAAUUAAGAGGAUACACACGUUUGUUUCUUCGUGCCUGUUUUAUGUGCACACAUUAGGCAUUGAGACUUCAAGCUUUUCUUUUUUUGUCCACGUAUCUUUGGGUCUUUGAUAAAGAAAAGAAUCCCUGUUCAUUGUAAGCACUUUUACGGGGCGGGUGGGGAGGGGUGCUCUGCUGGUCUUCAAUUACCAAGAAUUCUCCAAAACAAUUUUCUGCAGGAUGAUUGUACAGAAUCAUUGCUUAUGACAUGAUCGCUUUCUACACUGUAUUACAUAAAUAAAUUAAAUAAAAUAACCCCGGGCAAGACUUUUCUUUG2000000006AAGGAUGACUAC2000000006A2000000090GACAUUAAAUAAUCGAAGUAAUUUUGGGUGGGGAGAAGAGGCAGAUUCAAUUUUCU2000000009UUAACCAGUCUGAAGUUUCAUUUAUGAUACAAAAGAAGAUGAAAAUGGAAGUGGCAAUAUAAGGGGAUGAGGAAGGCAUGCCUGGACAAACCCUUCUUUUAAGAUGUGUCUUCAAUUUGUAUAAAAUGGUGUUUUCAUGUAAAUAAAUACAUUCUU

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	267	415	851	854	1121	1181	1347	1358	1456	1480	1866	1878	1879	1935
Modification Positions	Y	m6A	m6A	Y	m6A	Y	Y	Y	m6A	Y	m6A	m6A	Gm	Y
Genomic Coordinates	21:25954676:-	21:25911901:-	21:25891748:-	21:25891745:-	21:25881528:-	21:25881468:-	21:25881302:-	21:25881291:-	21:25881193:-	21:25881169:-	21:25880783:-	21:25880771:-	21:25880770:-	21:25880714:-
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	ArijeGVTwYBw BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	3kRDPWwiRCgi L6w2k2VEv4EY	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	dA7YoLwHrzgR ZuM5xpZmNuDL	3kRDPWwiRCgi L6w2k2VEv4EY	jaSvBXBkn3xs YkSG92k4EHDM	BtsJQJ3DteUq bXBqJigD9oV3 CxQaH6qDB9bC dknfVe6BK8aP eGNFqdoGxzRm kx7BHU7ZycYE Mk6ShCGm6RBJ oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8