Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: sugar
Atom address: 2′O
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
AviRb rRNA (uridine-2'-O-)-methyltransferase Streptomyces viridochromogenes
CMTR1 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Homo sapiens
CMTr2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 Homo sapiens
FBL rRNA 2′-O-methyltransferase fibrillarin Homo sapiens
MRM2 rRNA methyltransferase 2, mitochondrial Homo sapiens
Mrm2 Ribosomal RNA methyltransferase MRM2, mitochondrial Saccharomyces cerevisiae
Nop1 rRNA 2′-O-methyltransferase fibrillarin Saccharomyces cerevisiae
RlmE Ribosomal RNA large subunit methyltransferase E Escherichia coli
Spb1 AdoMet-dependent rRNA methyltransferase SPB1 Saccharomyces cerevisiae
Trm44 tRNA (uridine-O(2)-)-methyltransferase Saccharomyces cerevisiae
TrmJ tRNA (cytidine(32)/uridine(32)-2′-O)-methyltransferase Escherichia coli
TrmL tRNA (cytidine(34)-2′-O)-methyltransferase Escherichia coli
aTrm56 tRNA (cytidine(56)-2'-O)-methyltransferase Pyrococcus horikoshii

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