Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: sugar
Atom address: 2′O
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
CMTR1 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Homo sapiens
CMTr2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 Homo sapiens
FBL rRNA 2′-O-methyltransferase fibrillarin Homo sapiens
MRM1 rRNA methyltransferase 1, mitochondrial Homo sapiens
Mrm1 rRNA methyltransferase, mitochondrial Saccharomyces cerevisiae
Nop1 rRNA 2′-O-methyltransferase fibrillarin Saccharomyces cerevisiae
RNMTL1 RNA methyltransferase-like protein 1 Homo sapiens
RlmB Ribosomal RNA large subunit methyltransferase B Escherichia coli
RlmP 23S rRNA (guanosine(2553)-2'-O)-methyltransferase RlmP Bacillus subtilis
Spb1 AdoMet-dependent rRNA methyltransferase SPB1 Saccharomyces cerevisiae
Trm3 tRNA (guanosine(18)-2′-O)-methyltransferase Saccharomyces cerevisiae
Trm7 tRNA (cytidine(32)/guanosine(34)-2′-O)-methyltransferase Saccharomyces cerevisiae
TrmH tRNA (guanosine(18)-2′-O)-methyltransferase Escherichia coli
TrmH tRNA (guanosine(18)-2′-O)-methyltransferase Thermus thermophilus

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