Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: agmatinylation
Reaction type level 2: amination
Reaction type level 3: group addition
Input group: O
Output group: *NCCCCCCNC(=N)N
Introduced group name: agmatinyl
Introduced group type: polyamine
Site: base/endocyclic
Atom address: C2
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
TiaS tRNA(Ile2) 2-agmatinylcytidine synthase TiaS Archaeoglobus fulgidus
TiaS tRNA(Ile2) 2-agmatinylcytidine synthetase Haloferax volcanii
TiaS tRNA(Ile2) 2-agmatinylcytidine synthetase Pyrococcus horikoshii
 

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Publications

Title Authors Journal Details PubMed Id DOI
Structural basis of tRNA agmatinylation essential for AUA codon decoding. Osawa T, Kimura S, Terasaka N, Inanaga H, Suzuki T, Numata T Nat Struct Mol Biol [details] 22002223 -