Published on Jan. 1, 1997 in Nucleosides and Nucleotides volume 16:7-9, 955-958.

DOI: 10.1080/07328319708006114

Abstract:

The synthesis of all four phosphoramidites of 2’-O-rnethylthiomethyl ribonucleosides and their incorporation into hammerhead ribozymes and influence on nuclease stability and catalytic activity is described.