| Full name: | 18S rRNA aminocarboxypropyltransferase |
|---|---|
| Synonym: | PA14_17650 |
| UniProt: | Q12094 |
| Enzyme type: | |
| Position of modification - modification: |
:1191(None) - m1acp3Y |
| Level of experimental evidence: | 2 |
| Level of experimental reliability: | 2 |
MGKGKNKMHEPKNGRPQRGANGHSSRQNHRRMEMKYDNSEKMKFPVKLAMWDFDHCDPKRCSGKKLERLGLIKSLRVGQKFQGIVVSPNGKGVVCPDDLEIVEQHGASVVECSWARLEEVPFNKIGGKHERLLPYLVAANQVNYGRPWRLNCVEALAACFAIVGRMDWASELLSHFSWGMGFLELNKELLEIYQQCTDCDSVKRAEEEWLQKLEKETQERKSRAKEEDIWMMGNINRRGNGSQSDTSESEENSEQSDLEGNNQCIEYDSLGNAIRIDNMKSREAQSEESEDEESGSKENGEPLSYDPLGNLIR
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Y1191) in 18S rRNA
| Reaction | Substrate | SubstrateType | Position | (Anti)Codon | Modified (Anti)Codon | Amino Acid Change | Transcript Name | Transcript Region | Cellular Localization | References |
|---|---|---|---|---|---|---|---|---|---|---|
| m1Y:m1acp3Y | rRNA (r) | rRNA/rRNA/eukaryotic cytosol | 1191 |
| Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|
| Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans | Britta Meyer 1, Jan Philip Wurm 2, Sunny Sharma 3, Carina Immer 2, Denys Pogoryelov 4, Peter Kötter 1, Denis L J Lafontaine 3, Jens Wöhnert 5, Karl-Dieter Entian | [details] | 27084949 | 10.1093/nar/gkw244 |