Modomics - A Database of RNA Modifications

ID Card:

Full name: Uncharacterized tRNA/rRNA methyltransferase YfiF
Synonym: YfiF
GI: 84027944
Orf: yfiF, b2581
COG: COG0566
UniProt: P0AGJ5
Alpha Fold Predicted Structure: AF-P0AGJ5-F1
Enzyme type: methyltransferase predicted



Protein sequence:

MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRADGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEWWRQNKA

Comments:

Putative. Predicted to catalyze m2A37 formation in tRNA or 2′-O methylation.





Alpha Fold Predicted Structure:






Clear Selection and Reset Camera

Protein sequence:

M N D E M K G K S G K V K V M Y V R S D D D S D K R T H N P R T G K G G G R P G K S R A D G G R R P A R D D K Q S Q P R D R K W E D S P W R T V S R A P G D E T P E K A D H G G I S G K S F I D P E V L R R Q R A E E T R V Y G E N A C Q A L F Q S R P E A I V R A W F I Q S V T P R F K E A L R W M A A N R K A Y H V V D E A E L T K A S G T E H H G G V C F L I K K R N G T T V Q Q W V S Q A G A Q D C V L A L E N E S N P H N L G G M M R S C A H F G V K G V V V Q D A A L L E S G A A I R T A E G G A E H V Q P I T G D N I V N V L D D F R Q A G Y T V V T T S S E Q G K P L F K T S L P A K M V L V L G Q E Y E G L P D A A R D P N D L R V K I D G T G N V A G L N I S V A T G V L L G E W W R Q N K A

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P0AGJ5-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P0AGJ5-F1.cif  
DSSP Secondary Structures   P0AGJ5.dssp  





Publications:

Title Authors Journal Details PubMed Id DOI
Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases. Tkaczuk KL, Dunin-Horkawicz S, Purta E, Bujnicki JM BMC Bioinformatics [details] 17338813 -