Full name: | tRNA(pseudouridine54-N1)-methyltransferase |
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Synonym: | HVO_1989 |
GI: | 292656118 |
COG: | COG1901 |
UniProt: | D4GTL8 |
Structures: | | | |
Alpha Fold Predicted Structure: | AF-D4GTL8-F1 |
Enzyme type: | methyltransferase |
Position of modification - modification: |
t:54 - m1Y |
MRQFIVTGHDAPTTPDFSLDDIAGGAGRLDVLCRCVNSAFFLSHDIREDVRVHLVLGDEYTVRFEGSELRRLNPDERSTAALIRKALEKREEAIGHMPAESSPGVSIRRMGFETTLEEAASDATVVELHEDGDPVVQVEPPENPLFVLSDHHDFTDEEAELLAAAADERVRLGPEILHADHSITVAHNYLDTAGYSRY
AdoMet dependent methyltransferase. Pseudouridine in position 55 is important for efficient conversion of Psi54 to m1Psi54. This modification is located in the T-loop and is important for the tertiary structure of the tRNA molecule. Crystal structure of TrmY from M. jannaschii was solved at 1.4 and 1.55A resolution (see the entry for M. jannaschii TrmY).
Enter the variants
Position
Original
Variant
Alpha Fold Pdb Files | AF-D4GTL8-F1.pdb |
Alpha Fold Pdbx/mmCIF Files | AF-D4GTL8-F1.cif |
DSSP Secondary Structures | D4GTL8.dssp |
_PubMed_ |
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