Modomics - A Database of RNA Modifications


NameSystemic Lupus Erythematosus (A:I)
DescriptionUp-regulation of ADAR1 may be suppressing the ADAR2 function and results in hypo-editing in PDE8A1 gene transcripts of SLE T cells.
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptPDE8A1
Mapping TechnologyRT-PCR
Quantification techniquesRT-PCR, sequencing

Enzymes connected to Systemic Lupus Erythematosus:


Acronym Full name Enzyme Role Organism Comment
Exact modification enzyme yet to be verified. One or more ADAR enzymes involved, putatively.  
ID Title Authors Journal Details PubMed Id DOI
1412 Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes Robert J Orlowski, [details] 18462347 10.1111/j.1365-2567.2008.02850.x