Modomics - A Database of RNA Modifications


NameAmiothrophic Lateral Sclerosis (A:I)
DescriptionThe inefficient GluA2 Q/R site-editing by ADAR2 is one cause of motor neuron death in ALS.
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptGRIA2
Mapping TechnologyRT-PCR
Quantification techniquesRT-PCR, Restriction Digestion, sequencing

Enzymes connected to Amiothrophic Lateral Sclerosis:

Acronym Full name Enzyme Role Organism Comment
ADARB1 Double-stranded RNA-specific editase 1 None Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1403 Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons Takuto Hideyama [details] 22226999 10.1016/j.nbd.2011.12.033