Modomics - A Database of RNA Modifications


NamePancreatic cancer (A:m6A)
DescriptionIncreased KCNK15-AS1 lncRNA m6A methylation level is negatively correlated with KCNK15-AS1 expression and it sustains the proliferation, invasion and migration of pancreatic cancer cells. Decreased expression of ALKBH5 in pancreatic cancer cell determines an increased methylation of KCNK15-AS1 lncRNA, a decreased KCNK15-AS1 expression and an increased proliferation, migration and invasion of pancreatic cancer cells.
Related RNA reactionA:m6A
Found in RNAlncRNA
Modified TranscriptKCNK15-AS1
Mapping Technology
Quantification techniquesMeRIP RT-qPCR

Enzymes connected to Pancreatic cancer:

Acronym Full name Enzyme Role Organism Comment
ALKBH5 RNA demethylase ALKBH5 tumor-suppressor Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1106 ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation. Yuan He Cell Physiol Biochem [details] 30032148 10.1159/000491915