Modomics - A Database of RNA Modifications


NameNon-small cell lung cancer (A:m6A)
DescriptionALKBH5 is upregulated in the NSCLC tissue and cells. ALKBH5 induces the demethylation of TIMP3 transcript to repress its mRNA stability leading to NSCLC tumor progression
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptTIMP3
Mapping Technology
Quantification techniquesMeRIP-qPCR

Enzymes connected to Non-small cell lung cancer:

Acronym Full name Enzyme Role Organism Comment
ALKBH5 RNA demethylase ALKBH5 oncogene Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1095 N(6)-methyladenosine ALKBH5 promotes non-small cell lung cancer progress byregulating TIMP3 stability. Zhu Z Gene [details] 31927006 10.1016/j.gene.2020.144348