Name | Urothelial carcinoma of the bladder (UCB) (C:m5C) |
Description | NSUN2 and YBX1 stabilize the oncogene mRNA of the oncogene HDGF that mediates UCB pathogenesis in human |
Related RNA reaction | C:m5C |
Found in RNA | mRNA |
Modified Transcript | HDGF |
Mapping Technology | Bisulphite-seq |
Quantification techniques | UHPLC–MRM–MS/MS |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
NSUN2 | NOP2/Sun RNA methyltransferase 2 | oncogene | Homo sapiens | |
YBX1 | Y-box binding protein 1 | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1126 | 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs | Chen X | Nat Cell Biol . | [details] | 31358969 | 10.1038/s41556-019-0361-y |