| Name | Severe epilepsy (A:I) |
| Description | RNA editing in GluR-B is essential for brain development to avoid the alteration of calcium permeability which affects mice seizure and survival |
| Related RNA reaction | A:I |
| Found in RNA | mRNA |
| Modified Transcript | AMPAR GluA2 |
| Mapping Technology | |
| Quantification techniques | RT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ADARB1 | Double-stranded RNA-specific editase 1 | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1119 | Early-onset epilepsy and postnatal lethality associated with an editing-deficientGluR-B allele in mice. | Brusa R, Zimmermann F, Koh DS, Feldmeyer D, Gass P, Seeburg PH, Sprengel R | Science | [details] | 7502080 | 10.1126/science.270.5242.1677 |