Name | Ovarian and breast cancer (A:m1A) |
Description | CSF-1 expression is increased by the overexpression of ALKBH3. This results in cancer cell invasiveness without affecting cell proliferation and migration |
Related RNA reaction | A:m1A |
Found in RNA | mRNA |
Modified Transcript | CSF-1 |
Mapping Technology | m1A-MAP, MeRIP-seq |
Quantification techniques | qRT-PCR, IP-qRT-PCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ALKBH3 | alkB homolog 3, alpha-ketoglutarate dependent dioxygenase | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1102 | Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability inbreast and ovarian cancer cells. | Woo HH | Biochim Biophys Acta Gene Regul Mech | [details] | 30342176 | S1874-9399(18)30274-8 |