We currently offer two positions in the Bujnicki group in IIMCB, Warsaw, Poland

 

  1. PhD student position in experimental determination of RNA-protein complex structures   ( MAESTRO grant )
  2. PhD student position in software development, bioinformatics, molecular simulations and modeling



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red - jobs focused on software development (with some molecular modeling)
orange - jobs focused on modeling and data analyses (with some software development)
green - jobs focused on experimental biochemistry and biophysics

 


 

PhD student position in experimental determination of RNA-protein complex structures

 

We are looking for a junior scientist, interested in experimental structural biology combined with molecular modeling, and motivated to develop a career in an interdisciplinary and international team. 

The project "Integrative modeling and structure determination of RNA-protein complexes” (PI: prof. Janusz Bujnicki) is carried out as the MAESTRO 2017/26/A/NZ1/01083 grant of the Polish National Science Center, funded for 5 years. The PhD student will be selected from candidates in an open competition, according to the procedure complying with the rules for granting scholarships for young scientists in research projects funded by the National Science Centre (NCN Council Resolution No. 96/2016 dated. October 27, 2016 r.), with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers.

The main goals of the grant are: 1) Development of a software package for modeling of RNA, proteins and their complexes (based on our methods PyRy3D and SimRNA/SimRNP), and 2) Experimental analyses (including structure determination with a variety of biochemical and biophysical techniques, e.g., crystallography, SAXS, AFM, cryoEM) combined with computational modeling, to determine structures for macromolecular complexes. 

As a PhD student: You will be involved in experimental analyses of RNA, protein, and RNP 3D structures using various biochemical and biophysical techniques. You will collaborate with other researchers (theoreticians and experimentalists) within the team, in the institute, as well as with international partners. This project is for junior scientists interested in studying structures of biological macromolecules with various experimental methods and in interdisciplinary work that involves computational modeling based on experimental data.

Requirements: 

  • MSc degree (or equivalent) in biology, chemistry or related area - defended before the start of the work on the project and the first year of PhD studies (October 2018).
  • Eligibility for PhD studies in Poland under the supervision of prof. Bujnicki
  • Documented experience in biochemical and/or biophysical analyses of protein and/or nucleic acid structures. Experience in macromolecular crystallography, SAXS, AFM, cryoEM, biochemical probing of RNA structure and other related techniques will be advantageous.
  • Experience in bioinformatics is not essential, but knowledge of structure modeling tools will be advantageous. 
  • Proactive approach to achieving tasks and objectives, good interpersonal skills, collaborative attitude
  • Priority will be given to candidates with expertise most relevant to the project and to the profile of the laboratory. 

We offer:

  • PhD fellowship 4000 PLN/month, 
  • Appointment starting October 2018, fellowship guaranteed for 4 years
  • Position with 100% focus on research (no teaching obligations)
  • Participation in courses, scientific training, support from peers, and academic mentoring
  • Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme

How to apply:

  • We will collect applications until July 31st 2018 .
  • Apply now (or ask any questions you may have) to employment@genesilico.pl   
  • In the subject include "PhD-MAESTRO-RNPstructure" and your first and last name.
  • Your application must be in English and should contain a CV, a motivation letter (What is your scientific dream and how do you want to fulfill it? What are your key strengths? Why do you want to work with us?), a description of your key achievements, and contacts to at least two potential referees, including at least one direct supervisor. 
  • Please include the following statement in your application: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”
  • Best candidate(s) may be given additional questions and tasks before the final interview.The competition may be repeated until a suitable candidate who fulfills all requirements is found.

 

 


 

PhD student postion in software development, bioinformatics, molecular simulations and modeling

 

We are looking for a junior scientist, interested in software development, bioinformatics, molecular simulations and modeling, and motivated to develop a career in an interdisciplinary and international team.

The project “A coarse-grained method for RNA 3D structure modeling, with emphasis on non-canonical base pairing" (PI: dr. Michal Boniecki) is carried out as the OPUS 2016/23/B/ST6/03433 grant of the Polish National Science Center. The PhD student will be selected from candidates in an open competition, according to the procedure complying the rules for granting scholarships for young scientists in research projects funded by the National Science Centre (NCN Council Resolution No. 96/2016 dated. October 27, 2016 r.)

The goal of the project is to further develop SimRNA, which is now one of the best methods for 3D RNA structure prediction and simulations, in the field. We intend to improve the prediction of non-canonical base-pairs, and to improve the overall specificity. Additional tasks include RNA 3D structure prediction with additional restraints and setting up a web server. We provide opportunities for interdisciplinary collaborations within the team, in the institute, as well as with international partners.

Requirements: 

  • MSc in computer science, physics, chemistry or related area (defended before the start of the work on the project)
  • Eligibility for PhD studies in Poland
  • Documented experience in programming/designing in C/C++ and/or Python
  • Understanding issues of 3D geometry, derivation of statistical potentials, running simulations, working in Linux
  • Proactive approach to achieving tasks and objectives, good interpersonal skills, collaborative attitude
  • Experience in bioinformatics, molecular modeling etc. is advantageous, but not essential. 
  • Priority will be given to candidates with expertise most relevant to the project and to the profile of the laboratory.

We offer:

  • PhD fellowship 3000 PLN/month 
  • Position with 100% focus on research (no teaching obligations)
  • Participation in courses, scientific training, support from peers, and academic mentoring
  • Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme

How to apply:

  • We will collect applications until July 15th 2018
  • Apply now (or ask any questions you may have) to mboni@genesilico.pl In the subject include "PhD-SimRNA-devel" and your first and last name.
  • Your application must be in English and should contain a CV, a motivation letter (What are your key strengths? Why do you want to work with us? Your scientific dream?) preferably in one pdf file, below 5 MB, a description of your key achievements, and contacts to at least two potential referees, including at least one direct supervisor. 
  • Please include the following statement in your application: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”
  • Best candidate(s) may be given additional questions and tasks before the final interview.
  • The competition may be extended until a suitable candidate who fulfills all requirements is found.

 


 

Frequently asked questions:

 
Q: Is health insurance provided?
A: For postdoctoral and technician positions associated with a full work contract ("umowa o pracę"), full health insurance and social security (ZUS) is included. For undergraduate and gratuate students, and for volunteers, basic health insurance is provided, and if they wish, they may insure themselves individually to make their contribution to ZUS.
 
Q: Are references required?
A: Yes, references are an important part of the selection process and candidates for postdoctoral positions are asked to provide at least two names of referees (one name for students), including at least one former or current supervisor.
 
Q: I am not from Poland and I don't speak Polish. Am I eligible to apply?
A: Yes, IIMCB welcomes applications from outside Poland. IIMCB has an international culture, and the official working language is English.