We currently offer four positions in the Bujnicki group in IIMCB, Warsaw, Poland

 

  1. Postdoctoral fellow position in computational design and molecular modeling of RNA 3D structures
  2. PhD student position in design and experimental determination of RNA 3D structures
  3. PhD student position in computational design and molecular modeling of RNA 3D structures
  4. PhD student in development of simulation methods for RNA 3D structure prediction

 

 


 

Postdoctoral fellow position in computational design and molecular modeling of RNA 3D structures

 

We are looking for a postdoctoral fellow interested in bioinformatics software development and molecular modeling, motivated to lead a project and develop a career in an interdisciplinary and international team. 

The main goal of the OPUS project is to develop and test in practice a new method for designing RNA molecules that form desired structures and carry out desired functions. The project provides opportunities for extensive interdisciplinary collaborations within the team and in the institute (e.g. with software developers, molecular modelers, and experimentalists), as well as external collaborations with academia and industry. 

As a postdoctoral fellow in computational biology of RNA: You will be the leading scientist, the key developer of bioinformatics software in the OPUS project and you will be involved in computational design/modeling of RNA 3D structures. You will also assist in coordinating daily activities of the project team. Highly motivated individuals with the ability to pursue challenging tasks and achieve objectives are encouraged to apply.

Requirements: 

  • PhD in computer science, life sciences or related area
  • Documented experience in programming (Python and/or C/C++) 
  • Experience in molecular modeling, documented in publications (ideally experience in RNA modeling and design)
  • Organizational capabilities, creativity, proactive and collaborative attitude, communication and interpersonal skills,
  • Priority will be given to candidates with expertise most relevant to the project and to the profile of the laboratory. 

We offer:

  • full contract (umowa o pracę) 10 000 PLN/month total cost (~5 300 average net monthly salary), 
  • Position with 100% focus on research (no teaching obligations except for co-supervising students)
  • Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme
  • Appointment starting preferably in April 2018, funding guaranteed initially for 3 years, possible extension 
  • Participation in courses, scientific training, support from peers, and academic mentoring 

How to apply:

  • We will collect applications until February 28, 2018. Best candidates will be invited for an interview (In-Person or via Skype) early in March.
  • Apply now (or ask any questions you may have) to employment@genesilico.pl
  • In the subject include "postdoc-OPUS-RNAbioinfo" and your first and last name.Your application must be in English and should contain a CV, a motivation letter (What is your scientific dream and how do you want to fulfill it? What are your key strengths? Why do you want to work with us?), a description of your key achievements, and contacts to at least two potential referees, including at least one direct supervisor. 
  • Please include the following statement in your application: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”
  • The competition may be extended until a suitable candidate who fulfills all requirements is found.

The project "Development of new methods for designing RNA molecules that fold into desired spatial structures and their use for development of new functional RNAs and for prediction of noncoding RNAs in transcriptome sequences" is carried out as the OPUS grant of the Polish National Science Center.


 

PhD student position in design and experimental determination of RNA 3D structures

 

We are looking for a PhD student interested in molecular synthetic biology and/or structural biology, and motivated to develop a career in an interdisciplinary and international team. 

The main goal of the OPUS project is to develop and test in practice a new method for designing RNA molecules that form desired structures and carry out desired functions. The project provides opportunities for extensive interdisciplinary collaborations within the team and in the institute (e.g. with software developers, molecular modelers, and experimentalists), as well as external collaborations with academia and industry. 

As a PhD student in synthetic and structural biology of RNA: You will be involved in experimental validation of theoretical designs, production, and structural and functional characterization of novel RNA molecules. Highly motivated individuals with the ability to pursue challenging tasks and achieve objectives are encouraged to apply. 

Requirements: 

  • •Master’s degree in life sciences or related area (defended until June 2018 at the latest)
  • Eligibility for PhD studies in Poland under the supervision of prof. Bujnicki
  • Documented experience in biochemistry, structural biology, synthetic biology or nucleic acid chemistry
  • Proactive approach to achieving tasks and objectives, good interpersonal skills, collaborative attitude
  • Priority will be given to candidates with expertise most relevant to the project and to the profile of the laboratory. 

We offer:

  • PhD fellowship 3500 PLN/month 
  • Position with 100% focus on research (no teaching obligations)
  • Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme
  • Appointment starting between April and October 2018, funding guaranteed initially for 3 years, possible extension 
  •  Participation in courses, scientific training, support from peers, and academic mentoring 

How to apply:

  • We will collect applications until February 28, 2018. Best candidates will be invited for an interview (In-Person or via Skype) early in March.
  • Apply now (or ask any questions you may have) to employment@genesilico.pl   
  • In the subject include "PhD-OPUS-RNAstructure" and your first and last name.
  • Your application must be in English and should contain a CV, a motivation letter (What is your scientific dream and how do you want to fulfill it? What are your key strengths? Why do you want to work with us?), a description of your key achievements, and contacts to at least two potential referees, including at least one direct supervisor. 
  • Please include the following statement in your application: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”
  • The competition may be extended until a suitable candidate who fulfills all requirements is found.

The project "Development of new methods for designing RNA molecules that fold into desired spatial structures and their use for development of new functional RNAs and for prediction of noncoding RNAs in transcriptome sequences" is carried out as the OPUS grant of the Polish National Science Center. The PhD student will be selected from candidates in the open competition, according to the procedure complying the rules for granting scholarships for young scientists in research projects funded by the National Science Centre (NCN Council Resolution No. 96/2016 dated. October 27, 2016 r.)

 


 

PhD student position in computational design and molecular modeling of RNA 3D structures

 

We are looking for a PhD student interested in bioinformatics software development and molecular modeling, and motivated to develop a career in an interdisciplinary and international team. 

The main goal of the OPUS project is to develop and test in practice a new method for designing RNA molecules that form desired structures and carry out desired functions. The project provides opportunities for extensive interdisciplinary collaborations within the team and in the institute (e.g. with software developers, molecular modelers, and experimentalists), as well as external collaborations with academia and industry.

As a PhD student in computational biology of RNA: You will be involved in the combination of bioinformatics software development and in computational design/modeling of RNA 3D structures. Highly motivated individuals with the ability to pursue challenging tasks and achieve objectives are encouraged to apply.

Requirements: 

  • Master’s degree in computer science, life sciences or related area (defended until June 2018 at the latest)
  • Eligibility for PhD studies in Poland under the supervision of prof. Bujnicki
  • Documented experience in programming (Python and/or C/C++) and/or in molecular modeling
  • Proactive approach to achieving tasks and objectives, good interpersonal skills, collaborative attitude
  • Priority will be given to candidates with expertise most relevant to the project and to the profile of the laboratory. 

We offer:

  • PhD fellowship 3 500 PLN/month, 
  • Position with 100% focus on research (no teaching obligations)
  • Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme
  • Appointment starting between April and October 2018, funding guaranteed initially for 3 years, possible extension 
  • Participation in courses, scientific training, support from peers, and academic mentoring 

How to apply:

  • We will collect applications until February 28, 2018. Best candidates will be invited for an interview (In-Person or via Skype) early in March.
  • Apply now (or ask any questions you may have) to employment@genesilico.pl   
  • In the subject include "PhD-OPUS-RNAbioinfo" and your first and last name.
  • Your application must be in English and should contain a CV, a motivation letter (What is your scientific dream and how do you want to fulfill it? What are your key strengths? Why do you want to work with us?), a description of your key achievements, and contacts to at least two potential referees, including at least one direct supervisor. 
  • Please include the following statement in your application: "I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”
  • Best candidates will be invited for an interview early in March. The competition may be extended until a suitable candidate who fulfills all requirements is found.

The project "Development of new methods for designing RNA molecules that fold into desired spatial structures and their use for development of new functional RNAs and for prediction of noncoding RNAs in transcriptome sequences" is carried out as the OPUS grant of the Polish National Science Center. The PhD student will be selected from candidates in the open competition, according to the procedure complying the rules for granting scholarships for young scientists in research projects funded by the National Science Centre (NCN Council Resolution No. 96/2016 dated. October 27, 2016 r.)

 


 

PhD student in development of simulation methods for RNA 3D structure prediction


Description of the project:
The title of the project is: "A coarse-grained method for RNA 3D structure modeling, with emphasis on non-canonical base pairing". This will be further development of SimRNA. SimRNA is successful, already implemented and published method for RNA folding simulations and 3D structure prediction. (just google "SimRNA"). The main goal will be development towards better recapitulation of non-canonical base pairing, also improving overall prediction ability. The project also includes studies of folding RNA with restraints. Selected candidate will work together with PI (Michał Boniecki) (optionally with other lab members) on further development of SimRNA as well as investigate folding of RNA molecules. Typical tasks are (optionally, only some of them will be done by selected candidate):

  • development (programming) and testing of SimRNA and also other scripts or programs
  • running/setting up simulations, making structure predictions (of RNA molecules
  • studies of folding with restraints
  • processing results, making statistics
  • deriving statistical potentials (also preparing/filtering data sets of experimentally solved structures PDB)
  • optimization of parameters (at various levels/stages)
  • development of web server that runs SimRNA (in web server mode)
  • preparing conference materials (seminars, posters ...)
  • sharing of knowledge and experience

The project will be executed in prof. Janusz Bujnicki lab (www.genesilico.pl), Principle Investigator of the project will be dr Michał Boniecki.

Requirements:
Candidates with skills listed below will be preferred:

  • MSc in science or engineering (physics, chemistry, computer science, bioinformatics, biology or related)
  • understanding of basic concepts of dealing with / programming geometry 3D
  • programming/designing in languages: C/C++ (python will be an advantage)
  • understanding or/and experience in deriving statistical potentials (machine learning issues)
  • understanding or/and experience in optimization issues (in practice)
  • understanding of issues of folding of biomolecules (especially RNA)
  • understanding or/and Django framework
  • English, fluent spoken and written
  • creativity and dedication towards work and learning
  • good interpersonal skills, sharing knowledge and experience

Benefits:
We are an interdisciplinary team (www.genesilico.pl) that combines basic science (to solve the mysteries of nature) and applied science (to make the discoveries practically useful). In our laboratory, software developers meet with experimental biologists, and high-throughput data analysis combines with sophisticated studies of individual biomacromolecules. We develop new computational methods, new tools for biotechnology, and molecules that will hopefully become drugs against diseases. Our current research goals are based on a wild ambition: to understand the structure of all RNA molecules that exist, and design molecules that do not exist yet. We are hosted by IIMCB (http://iimcb.gov.pl), the top-ranked (A+) Polish research institute in biology. The institute provides cutting-edge equipment and facilities, in particular for bioinformatics/
Scholarship agreement, 3000 PLN per month netto.

How to apply:
Please send your CV and motivation letter (preferably as one PDF) to mboni@genesilico.pl (please do not send files bigger than 5 MB). Application should include a short statement of research interests, a brief description of scientific achievements (if applicable), and, if possible, contact information for one or two references. Questions about the position can be send to mboni@genesilico.pl or employment@genesilico.pl
Applications will be collected until 31 of July 2017.

In case no suitable candidates are found, we will continue collecting applications
Please include in your application the following statement: “In accordance with the personal data protection act from the 29th of August 1997, I hereby agree to process and to store my personal data by the Institution for recruitment purposes”.
The recruitment procedure fulfills the National Science Centre’s regulations on granting the scholarships to young scientists.

 


 

Frequently asked questions:

 
Q: Is health insurance provided?
A: For postdoctoral and technician positions associated with a full work contract ("umowa o pracę"), full health insurance and social security (ZUS) is included. For undergraduate and gratuate students, and for volunteers, basic health insurance is provided, and if they wish, they may insure themselves individually to make their contribution to ZUS.
 
Q: Are references required?
A: Yes, references are an important part of the selection process and candidates for postdoctoral positions are asked to provide at least two names of referees (one name for students), including at least one former or current supervisor.
 
Q: I am not from Poland and I don't speak Polish. Am I eligible to apply?
A: Yes, IIMCB welcomes applications from outside Poland. IIMCB has an international culture, and the official working language is English.