G-quadruplex unfolding in higher-order DNA structures
Overview of Fotticchia I et al.
| Authors | Fotticchia I Giancola C Petraccone L |
|---|---|
| Affiliation | Dipartimento di Scienze Farmaceutiche Università di Salerno Via Ponte Don Melillo 84084 Fisciano (SA) Italy. |
| Journal | Chem Commun (Camb) |
| Year | 2013 |
Abstract
G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.