Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: base/exocyclic
Atom address: N2
Modification level: 2

Enzymes that catalyse this reaction:

Acronym Full name Organism
Trm-G10 tRNA (guanine(10)-N2)-dimethyltransferase Pyrococcus abyssi
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase, mitochondrial Saccharomyces cerevisiae
Trm1 tRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase Aquifex aeolicus
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase Pyrococcus horikoshii
Trm1 tRNA (guanine(26)-N(2))-dimethyltransferase Homo sapiens

Image with reaction