Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: hydrogenation
Reaction type level 2: hydrogenation
Reaction type level 3: group addition
Input group: none
Output group: *H, *H
Introduced group name: hydrogen
Introduced group type: hydrogen
Site: base/endocyclic
Atom address: C5,C6
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
Dus1 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] Saccharomyces cerevisiae
Dus2 tRNA-dihydrouridine(20) synthase [NAD(P)+] Saccharomyces cerevisiae
Dus3 tRNA-dihydrouridine(47) synthase [NAD(P)(+)] Saccharomyces cerevisiae
Dus4 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+] Saccharomyces cerevisiae
DusA tRNA dihydrouridine synthase A Escherichia coli
DusB tRNA dihydrouridine synthase B Escherichia coli
DusC tRNA dihydrouridine synthase C Escherichia coli

Image with reaction