| Name | Renal cell carcinoma (A:m6A) |
| Description | In RCC cell lines and tissues, WTAP is significantly overexpressed. Mechanistic studies exhibited that CDK2 expression is positively associated with the expression of WTAP. Moreover, WTAP stabilizes CDK2 transcript to enhance CDK2 expression via binding to 3′-UTR of CDK2 transcript. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | CDK2 |
| Mapping Technology | |
| Quantification techniques |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| WTAP | Pre-mRNA-splicing regulator WTAP | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1117 | Wilms' tumor 1-associating protein promotes renal cell carcinoma proliferation by regulating CDK2 mRNA stability. | Jingyuan Tang | J Exp Clin Cancer Res | [details] | 29482572 | 10.1186/s13046-018-0706-6 |