| Name | Hepatocellular carcinoma (A:m6A) |
| Description | Snail, a key transcription factor of EMT, has an increased m6A methylation in its CDS and 3′UTR regions, through METTL3. m6A in CDS of Snail can trigger its translation elongation via interaction with YTHDF1 and eEF-2. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | Snail |
| Mapping Technology | MeRIP-seq |
| Quantification techniques | MeRIP-qPCR, m6A dot blot assay |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1039 | RNA mA methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. | Xinyao Lin | Nat Commun | [details] | 31061416 | 10.1038/s41467-019-09865-9 |