Modomics - A Database of RNA Modifications


NameGlioblastoma (A:I)
DescriptionReduction of RNA editing at the Q/R site of the GluRB induces loss of Ca2+ homeostasis suggests a role for RNA editing in tumor progression and may provide a molecular model explaining the occurrence of epileptic seizures in association with malignant gliomas.
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptGRIA2 (GLUR-B)
Mapping TechnologyRT-PCR
Quantification techniquesRT-PCR, sequencing

Enzymes connected to Glioblastoma:

Acronym Full name Enzyme Role Organism Comment
ADARB1 Double-stranded RNA-specific editase 1 None Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
969 Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Maas S Proc Natl Acad Sci U S A [details] 11717408 251531398