Modomics - A Database of RNA Modifications

Summary:

NameEsophageal squamous cell carcinoma (A:I)
DescriptionADARB1 is downregulated in In Esophageal Squamous Cell Carcinoma (ESCC). In normal tissue, ADARB1 suppresses tumor growth and induces apoptosis by editing and stabilizing IGFBP7.
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptIGFBP7
Mapping TechnologyRNA-seq
Quantification techniquesRT-PCR

Enzymes connected to Esophageal squamous cell carcinoma:

Acronym Full name Enzyme Role Organism Comment
ADARB1 Double-stranded RNA-specific editase 1 tumor-suppressor Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1015 ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma. Yuan-Bin Chen Int J Oncol [details] 28035363 10.3892/ijo.2016.3823