Modomics - A Database of RNA Modifications


NameHepatocellular carcinoma (A:I)
DescriptionHyper-editing of FLNB is closely associated with HCC pathogenesis. ADAR1 overexpression increases risk of liver cirrhosis and postoperative recurrence. ADAR1 hyper editing is associated with a poor prognosis
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptFLNB
Mapping Technologydirect sequemcing on PCR products
Quantification techniquesRT-PCR

Enzymes connected to Hepatocellular carcinoma:

Acronym Full name Enzyme Role Organism Comment
ADARB1 Double-stranded RNA-specific editase 1 oncogene Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1014 A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. Tim Hon Man Chan Gut [details] 23766440 10.1136/gutjnl-2012-304037