Modomics - A Database of RNA Modifications


NameLeukemia (A:m6A)
DescriptionReduced levels of METTL3/METTL14 may lead to pathogenesis and progression of E/R-positive acute lymphoblastic leukemia and increase relapse rates.
Related RNA reactionA:m6A
Modified Transcript
Mapping Technology
Quantification techniques

Enzymes connected to Leukemia:

Acronym Full name Enzyme Role Organism Comment
METTL14 N6-adenosine-methyltransferase non-catalytic subunit tumor-suppressor Homo sapiens
METTL3 N6-adenosine-methyltransferase 70 kDa subunit tumor-suppressor Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1061 The study of METTL3 and METTL14 expressions in childhood ETV6/RUNX1-positive acute lymphoblastic leukemia. Congcong Sun Mol Genet Genomic Med [details] 31429529 10.1002/mgg3.933