Modomics - A Database of RNA Modifications


NameHemoglobin E (N:Nm)
DescriptionHypermethylation of 4506 in 28S subunit of the ribosome leads to ribosome biogenesis deregulation
Related RNA reactionN:Nm
Found in RNArRNA
Modified Transcript28S rRNA - hypermethylation at position 4506 and 1858.
Mapping Technology
Quantification techniquesRT-qPCR

Enzymes connected to Hemoglobin E:

Acronym Full name Enzyme Role Organism Comment
FBL rRNA 2′-O-methyltransferase fibrillarin Homo sapiens
NOP58 NOP58 ribonucleoprotein Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1036 Hypermethylation of 28S ribosomal RNA in β-thalassemia trait carriers. Sornjai W Int J Biol Macromol [details] 27765567 S0141-8130(16)31101-1