Modomics - A Database of RNA Modifications


NameAcute Myeloid Leukemia (A:I)
DescriptionSplicing mutations affecting either the SH2 or PTPase domain of SHP-1 in motheaten and viable motheaten mice lead to multiple hematopoietic abnormalities, including the overexpansion and accumulation of myelomonocytic populations
Related RNA reactionA:I
Modified TranscriptmRNA
Mapping Technologyexome sequencing
Quantification techniquessemi-quantitative RT-PCR

Enzymes connected to Acute Myeloid Leukemia:

Acronym Full name Enzyme Role Organism Comment
ADARB1 Double-stranded RNA-specific editase 1 tumor-suppressor Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
961 RNA hyperediting and alternative splicing of hematopoietic cell phosphatase (PTPN6) gene in acute myeloid leukemia. A Beghini Hum Mol Genet [details] 11001933 -