DNAmoreDB - A Database of Deoxyribozymes

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Year of pub.	First Author	Laboratory	Title	PubMed ID	DOI	Reaction
1994	R R Breaker	G F Joyce	A DNA enzyme that cleaves RNA.	9383394	10.1016/1074-5521(94)90014-0	RNA cleavage
1995	R R Breaker	G F Joyce	A DNA enzyme with Mg(2+)-dependent RNA phosphoesterase activity.	9383471	10.1016/1074-5521(95)90028-4	RNA cleavage
1995	B Cuenoud	J W Szostak	A DNA metalloenzyme with DNA ligase activity.	7791880	10.1038/375611a0	DNA ligation
1996	Y Li	D Sen	A catalytic DNA for porphyrin metallation	None	10.1038/nsb0996-743	Porphyrin metalation
1996	D Faulhammer	M Famulok	The Ca2+ Ion as a Cofactor for a Novel RNA‐Cleaving Deoxyribozyme	None	10.1002/anie.199628371	RNA cleavage
1996	N Carmi	R R Breaker	In vitro selection of self-cleaving DNAs.	9000012	10.1016/s1074-5521(96)90170-2	DNA cleavage
1997	S W Santoro	G F Joyce	A general purpose RNA-cleaving DNA enzyme.	9113977	10.1073/pnas.94.9.4262	RNA cleavage
1997	C R Geyer	D Sen	Evidence for the metal-cofactor independence of an RNA phosphodiester-cleaving DNA enzyme.	9281526	10.1016/s1074-5521(97)90244-1	RNA cleavage
1997	D Faulhammer	M Famulok	Characterization and divalent metal-ion dependence of in vitro selected deoxyribozymes which cleave DNA/RNA chimeric oligonucleotides.	9191064	10.1006/jmbi.1997.1036	RNA cleavage
1997	Y Li	D Sen	Toward an efficient DNAzyme.	9154943	10.1021/bi962694n	Porphyrin metalation
1998	A Roth	R R Breaker	An amino acid as a cofactor for a catalytic polynucleotide.	9600911	10.1073/pnas.95.11.6027	RNA cleavage
1998	N Carmi	R R Breaker	Cleaving DNA with DNA.	9482868	10.1073/pnas.95.5.2233	DNA cleavage
1999	J Nowakowski	G F Joyce	Crystal structure of an 82-nucleotide RNA–DNA complex formed by the 10-23 DNA enzyme	None	10.1038/5839	RNA cleavage
1999	Y Li	R R Breaker	Phosphorylating DNA with DNA.	10077582	10.1073/pnas.96.6.2746	DNA phosphorylation
2000	A Peracchi		Preferential Activation of the 8–17 Deoxyribozyme by Ca2+ Ions EVIDENCE FOR THE IDENTITY OF 8–17 WITH THE CATALYTIC DOMAIN OF THE MG5 DEOXYRIBOZYME	None	10.1074/jbc.275.16.11693	RNA cleavage
2000	J Nowakowski	G F Joyce	Alternative conformations of a nucleic acid four-way junction.	10864501	10.1006/jmbi.2000.3826	RNA cleavage
2000	J Li	Y Lu	A Highly Sensitive and Selective Catalytic DNA Biosensor for Lead Ions	None	10.1021/ja0021316	RNA cleavage
2000	Y Li	R R Breaker	Capping DNA with DNA.	10715132	10.1021/bi992710r	DNA capping
2000	J Li	Y Lu	In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme.	10606646	10.1093/nar/28.2.481	RNA cleavage
2000	T L Sheppard	G F Joyce	A DNA enzyme with N-glycosylase activity.	10884411	10.1073/pnas.97.14.7802	DNA depurination
2000	S W Santoro	C F Barbas	RNA Cleavage by a DNA Enzyme with Extended Chemical Functionality	None	10.1021/ja993688s	RNA cleavage
2001	N Carmi	R R Breaker	Characterization of a DNA-cleaving deoxyribozyme.	11557347	10.1016/S0968-0896(01)00035-9	DNA cleavage
2001	D M Perrin	C Hélène	Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities.	11456753	10.1021/ja003290s	RNA cleavage
2001	A R Feldman	D Sen	A new and efficient DNA enzyme for the sequence-specific cleavage of RNA.	11800557	10.1006/jmbi.2001.5058	RNA cleavage
2002	W Wang	Y Li	Sequence diversity, metal specificity, and catalytic proficiency of metal-dependent phosphorylating DNA enzymes.	11983339	10.1016/S1074-5521(02)00127-8	DNA phosphorylation
2002	L Lermer	D M Perrin	Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines.	12188639	10.1021/ja0205075	RNA cleavage
2002	P Ordoukhanian	G F Joyce	RNA-cleaving DNA enzymes with altered regio- or enantioselectivity.	12381192	10.1021/ja027467p	RNA cleavage
2002	P J Bruesehoff	Y Lu	Improving metal ion specificity during in vitro selection of catalytic DNA.	12052183	10.2174/1386207023330264	RNA cleavage
2003	Y Wang	S K Silverman	Characterization of deoxyribozymes that synthesize branched RNA.	14690435	10.1021/bi0355847	RNA ligation
2003	Y Wang	S K Silverman	Deoxyribozymes that synthesize branched and lariat RNA.	12783536	10.1021/ja035150z	RNA ligation
2003	A Flynn-Charlebois	S K Silverman	In vitro evolution of an RNA-cleaving DNA enzyme into an RNA ligase switches the selectivity from 3'-5' to 2'-5'.	12720447	10.1021/ja0340331	RNA ligation
2003	B L Ricca	S K Silverman	Optimization and generality of a small deoxyribozyme that ligates RNA.	12860124	10.1016/S0022-2836(03)00654-5	RNA ligation
2003	A Flynn-Charlebois	S K Silverman	Deoxyribozymes with 2'-5' RNA ligase activity.	12603132	10.1021/ja028774y	RNA ligation
2003	Z Liu	Y Li	Assemblage of signaling DNA enzymes with intriguing metal-ion specificities and pH dependences.	12812493	10.1021/ja035208+	RNA cleavage
2003	M J Cairns	L‐Q Sun	Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites.	12771215	10.1093/nar/gkg378	RNA cleavage
2003	S H J Mei	Y Li	An efficient RNA-cleaving DNA enzyme that synchronizes catalysis with fluorescence signaling.	12517153	10.1021/ja0281232	RNA cleavage
2004	D J-F Chinnapen	D Sen	A deoxyribozyme that harnesses light to repair thymine dimers in DNA.	14691255	10.1073/pnas.0305943101	Thymine dimer repair
2004	T K Prior	S K Silverman	Structure-function correlations derived from faster variants of a RNA ligase deoxyribozyme.	14960718	10.1093/nar/gkh263	RNA ligation
2004	R L Coppins	S K Silverman	A DNA enzyme that mimics the first step of RNA splicing.	14758353	10.1038/nsmb727	RNA ligation
2004	R L Coppins	S K Silverman	Rational modification of a selection strategy leads to deoxyribozymes that create native 3'-5' RNA linkages.	15600344	10.1021/ja045817x	RNA ligation
2004	R P.G Cruz	Y Li	Dinucleotide Junction Cleavage Versatility of 8-17 Deoxyribozyme	None	10.1016/j.chembiol.2003.12.012	RNA cleavage
2004	M A Carrigan	S A Benner	Quantitative analysis of a RNA-cleaving DNA catalyst obtained via in vitro selection.	15350131	10.1021/bi049898l	RNA cleavage
2004	K Schlosser	Y Li	Tracing sequence diversity change of RNA-cleaving deoxyribozymes under increasing selection pressure during in vitro selection.	15274624	10.1021/bi049757j	RNA cleavage
2004	A V Sidorov	D M Williams	Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.	15004246	10.1093/nar/gkh326	RNA cleavage
2005	Y Wang	S K Silverman	Efficient one-step synthesis of biologically related lariat RNAs by a deoxyribozyme.	16086354	10.1002/anie.200501643	RNA ligation
2005	Y Wang	S K Silverman	Directing the outcome of deoxyribozyme selections to favor native 3'-5' RNA ligation.	15723545	10.1021/bi0478291	RNA ligation
2005	W E Purtha	S K Silverman	General deoxyribozyme-catalyzed synthesis of native 3'-5' RNA linkages.	16173722	10.1021/ja0533702	RNA ligation
2005	K A Hoadley	S K Silverman	Zn2+-dependent deoxyribozymes that form natural and unnatural RNA linkages.	15966746	10.1021/bi050146g	RNA ligation
2005	R L Coppins	S K Silverman	Mimicking the first step of RNA splicing: an artificial DNA enzyme can synthesize branched RNA using an oligonucleotide leaving group as a 5'-exon analogue.	16216067	10.1021/bi0507229	RNA ligation
2005	R L Coppins	S K Silverman	A deoxyribozyme that forms a three-helix-junction complex with its RNA substrates and has general RNA branch-forming activity.	15740125	10.1021/ja044881b	RNA ligation
2005	D R Semlow	S K Silverman	Parallel selections in vitro reveal a preference for 2'-5' RNA ligation upon deoxyribozyme-mediated opening of a 2',3'-cyclic phosphate.	16007488	10.1007/s00239-004-0326-y	RNA ligation
2005	E D Pratico	S K Silverman	A deoxyribozyme that synthesizes 2',5'-branched RNA with any branch-site nucleotide.	15967808	10.1093/nar/gki656	RNA ligation
2005	J C Achenbach	Y Li	Secondary-structure characterization of two proficient kinase deoxyribozymes.	15751953	10.1021/bi0483054	DNA phosphorylation
2005	A Peracchi	M Clerici	A mutational analysis of the 8-17 deoxyribozyme core.	16125199	10.1016/j.jmb.2005.07.059	RNA cleavage
2005	K E Nelson	Y Lu	In vitro selection of high temperature Zn(2+)-dependent DNAzymes.	16096680	10.1007/s00239-004-0374-3	RNA cleavage
2006	N Paul	G F Joyce	Conversion of a ribozyme to a deoxyribozyme through in vitro evolution.	16638538	10.1016/j.chembiol.2006.01.007	RNA ligation
2006	E Zelin	Scott K Silverman	Adenosine is inherently favored as the branch-site RNA nucleotide in a structural context that resembles natural RNA splicing.	16503631	10.1021/bi052499l	RNA ligation
2006	W Chiuman	Y Li	Revitalization of six abandoned catalytic DNA species reveals a common three-way junction framework and diverse catalytic cores.	16480741	10.1016/j.jmb.2006.01.036	RNA cleavage
2006	W Chiuman	Y Li	Evolution of high-branching deoxyribozymes from a catalytic DNA with a three-way junction.	17052610	10.1016/j.chembiol.2006.08.009	RNA cleavage
2006	K Schlosser	Y Li	Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: the effect of excess sequence elements on the outcome of in vitro selection.	16682452	10.1093/nar/gkl276	RNA cleavage
2007	C Höbartner	S K Silverman	Site-selective depurination by a periodate-dependent deoxyribozyme.	17534508	10.1039/b704507g	DNA depurination
2007	C Höbartner	S K Silverman	Engineering a selective small-molecule substrate binding site into a deoxyribozyme.	17694519	10.1002/anie.200702217	RNA ligation
2007	D J-F Chinnapen	D Sen	Towards elucidation of the mechanism of UV1C, a deoxyribozyme with photolyase activity.	17141270	10.1016/j.jmb.2006.10.062	Thymine dimer repair
2007	J Liu	Y Lu	A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity.	17284609	10.1073/pnas.0607875104	RNA cleavage
2007	W Chiuman	Y Li	Simple fluorescent sensors engineered with catalytic DNA 'MgZ' based on a non-classic allosteric design.	18030352	10.1371/journal.pone.0001224	RNA cleavage
2008	T P Mui	S K Silverman	Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA.	18808125	10.1021/ol801568q	DNA ligation
2008	P I Pradeepkumar	Scott K Silverman	DNA-catalyzed formation of nucleopeptide linkages.	18214866	10.1002/anie.200703676	Covalent Modification of Amino Acid Side Chains RNA ligation
2008	D M Kost	S K Silverman	Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2',3'-cyclic phosphate RNA substrates.	19005599	10.1039/B813566E	RNA ligation
2008	M Hollenstein	D M Perrin	A Highly Selective DNAzyme Sensor for Mercuric Ions	None	10.1002/anie.200800960	RNA cleavage
2008	M Chandra	S K Silverman	DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation.	18271591	10.1021/ja7111965	Diels-Alder
2008	K Schlosser	Y Li	Sequence-function relationships provide new insight into the cleavage site selectivity of the 8–17 RNA-cleaving deoxyribozyme	None	10.1093/nar/gkm1175	RNA cleavage
2008	K Schlosser	J Gu, L Sule	Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme	None	10.1093/nar/gkm1175	RNA cleavage
2008	K Schlosser	Y Li	In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions.	18644842	10.1093/nar/gkn396	RNA cleavage
2009	R E Thorne	D Sen	A deoxyribozyme, Sero1C, uses light and serotonin to repair diverse pyrimidine dimers in DNA.	19281822	10.1016/j.jmb.2009.02.064	Thymine dimer repair
2009	G S Sekhon	D Sen	Unusual DNA-DNA cross-links between a photolyase deoxyribozyme, UV1C, and its bound oligonucleotide substrate.	19514779	10.1021/bi900531z	Thymine dimer repair
2009	M Chandra	S K Silverman	DNA-catalyzed sequence-specific hydrolysis of DNA	None	10.1038/nchembio.201	DNA cleavage
2009	K Schlosser	Y Li	DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides.	19050014	10.1093/nar/gkn930	RNA cleavage
2009	A K Brown	Y Lu	Biochemical characterization of a uranyl ion-specific DNAzyme.	19142882	10.1002/cbic.200800632	RNA cleavage
2009	M Hollenstein	D M Perrin	A DNAzyme with three protein-like functional groups: enhancing catalytic efficiency of M2+-independent RNA cleavage.	19591189	10.1002/cbic.200900314	RNA cleavage
2009	M Hollenstein	D M Perrin	A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+).	19153138	10.1093/nar/gkn1070	RNA cleavage
2010	F Wachowius	C Höbartner	Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis.	20872387	10.1002/anie.201003940	RNA ligation
2010	A Sachdeva	S K Silverman	DNA-catalyzed serine side chain reactivity and selectivity.	20234910	10.1039/b927317d	Covalent Modification of Amino Acid Side Chains
2010	Y Xiao	S K Silverman	Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme.	20923239	10.1021/bi1013672	DNA cleavage
2010	J C F Lam	Y Li	A complex RNA-cleaving DNAzyme that can efficiently cleave a pyrimidine-pyrimidine junction.	20630470	10.1016/j.jmb.2010.05.047	RNA cleavage
2011	F Wachowius	C Höbartner	Probing essential nucleobase functional groups in aptamers and deoxyribozymes by nucleotide analogue interference mapping of DNA.	21863810	10.1021/ja205894w	RNA ligation
2011	Y Xiao	S K Silverman	Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn2+-only) behavior.	21125108	10.1039/c0cc04575f	DNA cleavage
2011	O Y Wong	S K Silverman	DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.	21510668	10.1021/bi200585n	Covalent Modification of Amino Acid Side Chains
2011	C S Lee	S K Silverman	Improved deoxyribozymes for synthesis of covalently branched DNA and RNA.	20739352	10.1093/nar/gkq753	RNA ligation DNA ligation
2011	O Y Wong	S K Silverman	DNA-catalyzed reductive amination.	21994131	10.1002/anie.201104976	Reductive amination
2011	M M Ali	Y Li	Fluorogenic DNAzyme probes as bacterial indicators.	21412961	10.1002/anie.201100477	RNA cleavage
2011	C J Hipolito	D M Perrin	Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes.	21311779	10.1039/c0ob00595a	RNA cleavage
2012	T E Velez	S K Silverman	Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length.	23088677	10.1021/co300111f	DNA cleavage Covalent Modification of Amino Acid Side Chains
2012	A Sachdeva	S K Silverman	Covalent tagging of phosphorylated peptides by phosphate-specific deoxyribozymes.	22315198	10.1002/cbic.201200048	Covalent Modification of Phosphorylated Amino Acid Side Chains
2012	A Sachdeva	S K Silverman	DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.	22042295	10.1039/c1ob06088k	Covalent Modification of Amino Acid Side Chains
2012	Y Xiao	S K Silverman	Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA.	22021383	10.1093/nar/gkr860	DNA cleavage
2012	V Dokukin	S K Silverman	Lanthanide ions as required cofactors for DNA catalysts	None	10.1039/C2SC01067D	DNA cleavage
2012	K E Nelson	Y Lu	The importance of peripheral sequences in determining the metal selectivity of an in vitro-selected Co(2+) -dependent DNAzyme.	22250000	10.1002/cbic.201100724	RNA cleavage
2013	J Chandrasekar	S K Silverman	Catalytic DNA with phosphatase activity.	23509279	10.1073/pnas.1221946110	Dephosphorylation
2013	S M Walsh	S K Silverman	DNA catalysts with tyrosine kinase activity.	24066831	10.1021/ja407586u	Tyrosine Phosphorylation
2013	D J Parker	S K Silverman	DNA catalysis of a normally disfavored RNA hydrolysis reaction.	23697866	10.1021/ja4032488	RNA cleavage
2013	J Yang	M T Bowser	Capillary electrophoresis-SELEX selection of catalytic DNA aptamers for a small-molecule porphyrin target.	23234289	10.1021/ac302721j	Porphyrin metalation
2013	B M Brandsen	S K Silverman	DNA-catalyzed hydrolysis of esters and aromatic amides.	24127695	10.1021/ja4077233	Ester hydrolysis Amide hydrolysis
2013	A K Behera	A Baum	Enhanced deoxyribozyme‐catalyzed RNA ligation in the presence of organic cosolvents	None	10.1002/bip.22191	RNA ligation
2013	F Javadi-Zarnaghi		Lanthanide cofactors accelerate DNA-catalyzed synthesis of branched RNA.	23895365	10.1021/ja406162z	RNA ligation
2013	H Gu	R R Breaker	Small, highly active DNAs that hydrolyze DNA.	23679108	10.1021/ja403585e	DNA cleavage
2013	P Wu	Y Lu	A DNAzyme-gold nanoparticle probe for uranyl ion in living cells.	23531046	10.1021/ja400150v	RNA cleavage
2013	M Hollenstein	D M Perrin	Toward the combinatorial selection of chemically modified DNAzyme RNase A mimics active against all-RNA substrates.	23485334	10.1021/co3001378	RNA cleavage
2014	C Chu	S K Silverman	A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation.	25056930	10.1002/cbic.201402255	Covalent Modification of Amino Acid Side Chains
2014	V Dokukin	S K Silverman	A modular tyrosine kinase deoxyribozyme with discrete aptamer and catalyst domains.	25000337	10.1039/c4cc04253k	Tyrosine Phosphorylation
2014	B M Brandsen	S K Silverman	DNA-catalyzed lysine side chain modification.	24981820	10.1002/anie.201404622	Covalent Modification of Amino Acid Side Chains
2014	P-J J Huang	J Liu	Ultrasensitive DNAzyme beacon for lanthanides and metal speciation.	24383540	10.1021/ac403762s	RNA cleavage
2014	P-J J Huang	J Liu	In vitro selection of a new lanthanide-dependent DNAzyme for ratiometric sensing lanthanides.	25199650	10.1021/ac5029962	RNA cleavage
2014	M Wang	Z Tang	In vitro selection of DNA-cleaving deoxyribozyme with site-specific thymidine excision activity.	25030901	10.1093/nar/gku592	DNA cleavage
2015	J Chandrasekar	S K Silverman	Phosphoserine Lyase Deoxyribozymes: DNA-Catalyzed Formation of Dehydroalanine Residues in Peptides.	26200899	10.1021/jacs.5b06308	Covalent Modification of Phosphorylated Amino Acid Side Chains
2015	S M Walsh	S K Silverman	Identification of Sequence-Selective Tyrosine Kinase Deoxyribozymes.	26407964	10.1007/s00239-015-9699-3	Tyrosine Phosphorylation
2015	S-F Torabi	Y Lu	In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing	None	10.1073/pnas.1420361112	RNA cleavage
2015	S-F Torabi	Y Lu	Identification of the Same Na(+)-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions.	26577294	10.1007/s00239-015-9715-7	RNA cleavage
2015	R Saran	J Liu	Searching for a DNAzyme Version of the Leadzyme.	26458991	10.1007/s00239-015-9702-z	RNA cleavage
2015	M Vazin	J Liu	Biochemical Characterization of a Lanthanide-Dependent DNAzyme with Normal and Phosphorothioate-Modified Substrates.	26356231	10.1021/acs.biochem.5b00691	RNA cleavage
2015	P-J J Huang	J Liu	A new heavy lanthanide-dependent DNAzyme displaying strong metal cooperativity and unrescuable phosphorothioate effect.	25488814	10.1093/nar/gku1296	RNA cleavage
2015	P-J J Huang	J Liu	Desulfurization Activated Phosphorothioate DNAzyme for the Detection of Thallium.	26393365	10.1021/acs.analchem.5b02568	RNA cleavage
2015	W Zhou	J Liu	A New Na+‐Dependent RNA‐Cleaving DNAzyme with over 1000‐fold Rate Acceleration by Ethanol	None	10.1002/cbic.201500603	RNA cleavage
2015	P-J J Huang	J Liu	Rational evolution of Cd2+-specific DNAzymes with phosphorothioate modified cleavage junction and Cd2+ sensing.	25990730	10.1093/nar/gkv519	RNA cleavage
2015	Rachel Gysbers	Y Li	Evolution of an Enzyme from a Noncatalytic Nucleic Acid Sequence.	26091540	10.1038/srep11405	RNA cleavage
2015	K Tram	Y Li	An Efficient Catalytic DNA that Cleaves L-RNA.	25946137	10.1371/journal.pone.0126402	RNA cleavage
2016	A Barlev	D Sen	DNA Repair by DNA: The UV1C DNAzyme Catalyzes Photoreactivation of Cyclobutane Thymine Dimers in DNA More Effectively than Their de Novo Formation.	27726378	10.1021/acs.biochem.6b00951	Thymine dimer repair
2016	A Ponce-Salvatierra	V Pena	Crystal structure of a DNA catalyst.	26735012	10.1038/nature16471	RNA ligation
2016	R Saran	J Liu	A Silver DNAzyme.	26977895	10.1021/acs.analchem.6b00327	RNA cleavage
2016	P Wang	S K Silverman	DNA-Catalyzed Introduction of Azide at Tyrosine for Peptide Modification.	27391404	10.1002/anie.201604364	Tyrosine azido‐adenylylation
2016	A J Camden	S K Silverman	DNA Oligonucleotide 3'-Phosphorylation by a DNA Enzyme.	27063020	10.1021/acs.biochem.6b00151	DNA phosphorylation
2016	C Chu	S K Silverman	Assessing histidine tags for recruiting deoxyribozymes to catalyze peptide and protein modification reactions.	27138704	10.1039/c6ob00716c	Tyrosine Phosphorylation Covalent Modification of Amino Acid Side Chains
2016	C Zhou	S K Silverman	DNA-Catalyzed Amide Hydrolysis.	26854515	10.1021/jacs.5b12647	Amide hydrolysis
2016	A R Hesser	S K Silverman	DNA-catalyzed glycosylation using aryl glycoside donors.	27355482	10.1039/c6cc04329a	Glycosylation
2016	A Kasprowicz	J Ciesiołka	Characterization of Highly Efficient RNA‐Cleaving DNAzymes that Function at Acidic pH with No Divalent Metal‐Ion Cofactors	None	10.1002/open.201600141	RNA cleavage
2016	W Zhou	J Liu	A DNAzyme requiring two different metal ions at two distinct sites.	26657636	10.1093/nar/gkv1346	RNA cleavage
2016	W Zhou	J Liu	An Efficient Lanthanide-Dependent DNAzyme Cleaving 2'-5'-Linked RNA.	26957420	10.1002/cbic.201500690	RNA cleavage
2016	Z Shen	Y Li	A Catalytic DNA Activated by a Specific Strain of Bacterial Pathogen.	26676768	10.1002/anie.201510125	RNA cleavage
2016	P-J J Huang	J Liu	Distinction of Individual Lanthanide Ions with a DNAzyme Beacon Array	None	10.1021/acssensors.6b00239	RNA cleavage
2016	W Zhou	J Liu	In Vitro Selection of Chromium-Dependent DNAzymes for Sensing Chromium(III) and Chromium(VI).	27249536	10.1002/chem.201601426	RNA cleavage
2016	P-J J Huang	J Liu	In Vitro Selection of a DNAzyme Cooperatively Binding Two Lanthanide Ions for RNA Cleavage.	27054549	10.1021/acs.biochem.6b00132	RNA cleavage
2016	P-J J Huang	J Liu	An Ultrasensitive Light-up Cu(2+) Biosensor Using a New DNAzyme Cleaving a Phosphorothioate-Modified Substrate.	26857405	10.1021/acs.analchem.5b04904	RNA cleavage
2017	H Liu	J Gan	Crystal structure of an RNA-cleaving DNAzyme.	29222499	10.1038/s41467-017-02203-x	RNA cleavage
2017	Y Lee	S K Silverman	DNA-Catalyzed DNA Cleavage by a Radical Pathway with Well-Defined Products.	27935689	10.1021/jacs.6b10274	DNA cleavage
2017	R Saran	J Liu	A Silver-Specific DNAzyme with a New Silver Aptamer and Salt-Promoted Activity.	28345892	10.1021/acs.biochem.6b01131	RNA cleavage
2017	W Zhou	J Liu	Two Completely Different Mechanisms for Highly Specific Na+ Recognition by DNAzymes	None	10.1002/cbic.201700184	RNA cleavage
2017	W Zhou	J Liu	An Exceptionally Selective DNA Cooperatively Binding Two Ca Ions.	28087991	10.1002/cbic.201600708	RNA cleavage
2018	A Barlev	D Sen	DNA's Encounter with Ultraviolet Light: An Instinct for Self-Preservation?	29419284	10.1021/acs.accounts.7b00582	Thymine dimer repair
2018	M V Sednev	C Höbartner	N -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes.	30276938	10.1002/anie.201808745	RNA cleavage
2018	L Gu	J Liu	Reselection Yielding a Smaller and More Active Silver-Specific DNAzyme.	31458180	10.1021/acsomega.8b02039	RNA cleavage
2018	T Yu	J Liu	An RNA-Cleaving Catalytic DNA Accelerated by Freezing.	29537685	10.1002/cbic.201800049	RNA cleavage
2018	Y Wang	D M Perrin	A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover	None	10.1039/C7SC04491G	RNA cleavage
2019	J Aranda	M Orozco	An artificial DNAzyme RNA ligase shows a reaction mechanism resembling that of cellular polymerases	None	10.1038/s41929-019-0290-y	RNA ligation
2019	D Peng	J Liu	Efficient DNA-Catalyzed Porphyrin Metalation for Fluorescent Ratiometric Pb Detection.	31414597	10.1021/acs.analchem.9b02759	Porphyrin metalation
2019	E J Mattioli	M Calvaresi	DNAzymes at Work: A DFT Computational Investigation on the Mechanism of 9DB1	None	10.1021/acs.jcim.8b00815	RNA ligation
2019	L Ma	J Liu	From general base to general acid catalysis in a sodium-specific DNAzyme by a guanine-to-adenine mutation	None	10.1093/nar/gkz578	RNA cleavage
2019	L Ma	J Liu	An in Vitro-Selected DNAzyme Mutant Highly Specific for Na under Slightly Acidic Conditions.	29989277	10.1002/cbic.201800322	RNA cleavage
2019	Y Wang	H Yu	A Novel Small RNA-Cleaving Deoxyribozyme with a Short Binding Arm	None	10.1038/s41598-019-44750-x	RNA cleavage
2019	P-J J Huang	J Liu	Instantaneous Iodine-Assisted DNAzyme Cleavage of Phosphorothioate RNA.	30272443	10.1021/acs.biochem.8b00900	RNA cleavage
2019	L Yang	R Pei	Exploration of Catalytic Nucleic Acids on Porphyrin Metalation and Peroxidase Activity by in Vitro Selection of Aptamers for N-Methyl Mesoporphyrin IX.	30602113	10.1021/acscombsci.8b00129	Porphyrin metalation
2020	H Yang	J Liu	Pb2+ as a Substrate and a Cofactor of a Porphyrin Metalation DNAzyme.	32202058	10.1002/cbic.202000073	Porphyrin metalation
2020	A Liaqat	C Höbartner	N 6-isopentenyladenosine in RNA determines the cleavage site of endonuclease deoxyribozymes.	32681686	10.1002/anie.202006218	RNA cleavage
2020	K Liu	D Sen	CLICK-17, a DNA enzyme that harnesses ultra-low concentrations of either Cu+ or Cu2+ to catalyze the azide-alkyne 'click' reaction in water.	32520335	10.1093/nar/gkaa502	Copper-mediated Azide-Alkyne Cycloaddition (CuAAC)
2020	H Rosenbach	I Span	Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity.	32646019	10.3390/molecules25133100
2020	C P M Scheitl	C Höbartner	New Deoxyribozymes for the Native Ligation of RNA.	32796587	10.3390/molecules25163650	RNA ligation
2020	W Ren	J Liu	Selection of a metal ligand modified DNAzyme for detecting Ni.	32510338	10.1016/j.bios.2020.112285	RNA cleavage
2020	P-J J Huang	J Liu	Target Self-Enhanced Selectivity in Metal-Specific DNAzymes.	31867832	10.1002/anie.201915675	RNA cleavage

Showing 1 to 166 of 166 entries

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