Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | RNA cleavage |
Group 1 - 2'-OH Group 2 - vicinal phosphate |
X: m6A S: AUAGACUGAAUGAAGGXCUUCCGUAACU |
n.d. |
Mg2+ |
RNA phosphodiester | N 20 |
---|
Buffer conditions |
---|
50 mM Tris-HCl pH 7.5, 150 mM NaCl, 5 mM MgCl2 |
Catalytic region of the DNAzyme |
---|
GATTCCAGGGCTTGAGGAGG |
Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
---|---|---|---|---|---|---|
2018 | M V Sednev | C Höbartner | N -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes. | 30276938 | 10.1002/anie.201808745 | RNA cleavage |