| Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | RNA ligation |
Group 1 - 2',3'-diol Group 2 - 5'-triphosphate |
L: UAAUACGACUCACUAUA R: GGAAGAGAUGGCGACGG |
native RNA |
Mg2+ |
3',5' | N 38 |
|---|
| Buffer conditions |
|---|
| 50 mM CHES pH 9.0, 150 mM NaCl, 2 mM KCl, 40 mM MgCl2 |
| Catalytic region of the DNAzyme |
|---|
| CACAAGGGAACAGGCTGCGTGTGAGAGAGTCGCGGTAA |
| Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
|---|---|---|---|---|---|---|
| 2004 | R L Coppins | S K Silverman | Rational modification of a selection strategy leads to deoxyribozymes that create native 3'-5' RNA linkages. | 15600344 | 10.1021/ja045817x | RNA ligation |