| Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | RNA ligation |
Group 1 - 2',3 '- diol Group 2 - 5'-triphosphate |
L: GGAAGUCUCAUGUACUAUCG R: GAAUGUUCUAGCGCGGA |
native RNA |
Mn2+ |
3',5' | N 40 |
|---|
| Buffer conditions |
|---|
| 50 mM HEPES pH 7.5, 150 mM NaCl, 2 mM KCl, 20 mM MnCl2 |
| Catalytic region of the DNAzyme |
|---|
| CCCGTGCACTCTATGATGGTGTCCCCTGATACCAACAGGG |
| Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
|---|---|---|---|---|---|---|
| 2005 | Y Wang | S K Silverman | Directing the outcome of deoxyribozyme selections to favor native 3'-5' RNA ligation. | 15723545 | 10.1021/bi0478291 | RNA ligation |