DNAmoreDB - A Database of Deoxyribozymes

DNAzyme description

 Reaction  Reacting groups Product  Metal ion Linkage  Seq description
RNA cleavage Group 1 - 2'-OH of rA

Group 2 - vicinal phosphate

inactive Gd3+
RNA phosphodiester N 50
 Buffer conditions
10 µM Gd3+, 50 mM MES pH 6.0, 25 mM NaCl
 Catalytic region of the DNAzyme
TTTCGCCATCTTGACGCATAGCACGTGTTAGTGACTCGT
Notes
Truncated version of Gd2.

 Reported in...

Year of Publication First Author Laboratory Title PubMed ID DOI Reaction
2016 P-J J Huang J Liu Distinction of Individual Lanthanide Ions with a DNAzyme Beacon Array None 10.1021/acssensors.6b00239 RNA cleavage

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