Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | RNA cleavage |
Group 1 - 2'-OH of rU Group 2 - vicinal phosphate |
S: AAAAGUAACUAGAGAUGG |
specific cleavage at desired position |
Mg2+ |
RNA phosphodiester | N 50 |
---|
Buffer conditions |
---|
1 M NaCl, 50 mM Tris-HCl pH 7.5, 10 mM MgCl2 |
Catalytic region of the DNAzyme |
---|
TGTTTCTCGCTTTGCTGGATGTACTTTT |
Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
---|---|---|---|---|---|---|
2019 | Y Wang | H Yu | A Novel Small RNA-Cleaving Deoxyribozyme with a Short Binding Arm | None | 10.1038/s41598-019-44750-x | RNA cleavage |