Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | RNA cleavage |
Group 1 - 2'-OH of rA Group 2 - vicinal phosphate |
S: * |
specific cleavage at desired position |
Ce3+ |
RNA phosphodiester | N * |
---|
Buffer conditions |
---|
* |
Catalytic region of the DNAzyme |
---|
TTTCGCCATCTTTACAAGGAAGGATGCACAACGGTTATAGTGACTCGTGAC |
Notes |
---|
Truncated DNAzymes derived from Lu1 (trans-cleaving) |
Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
---|---|---|---|---|---|---|
2014 | P-J J Huang | J Liu | In vitro selection of a new lanthanide-dependent DNAzyme for ratiometric sensing lanthanides. | 25199650 | 10.1021/ac5029962 | RNA cleavage |