| Reaction | Reacting groups | Substrates | Metal ion | Linkage | Seq description | RNA cleavage |
Group 1 - 2'-OH of rA Group 2 - vicinal phosphate |
S: GTCACGAGTCACTATrAGGAAGATGGCGAAA |
Ag+ |
RNA phosphodiester | N * |
|---|
| Buffer conditions |
|---|
| pH 7.5, 200 mM NaNO3, 10 μM AgNO3 |
| Yield (%) | kcat/ kobs |
|---|---|
| 60 | kobs = 0.41 min-1 |
| Catalytic region of the DNAzyme |
|---|
| TAGGTGATTTCCACGATTATGCGGAAACAGGGCAGCGT |
| Notes |
|---|
| Truncated version of Ag10 |
| Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
|---|---|---|---|---|---|---|
| 2016 | R Saran | J Liu | A Silver DNAzyme. | 26977895 | 10.1021/acs.analchem.6b00327 | RNA cleavage |
| Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
|---|---|---|---|---|---|---|
| 2017 | R Saran | J Liu | A Silver-Specific DNAzyme with a New Silver Aptamer and Salt-Promoted Activity. | 28345892 | 10.1021/acs.biochem.6b01131 |
RNA cleavage |