| Reaction | Reacting groups | Substrates | Product | Metal ion | Linkage | Seq description | DNA cleavage |
Group 1 - H2O |
S: CTACCTTTATGCGTATCGAAGGAGGCTTTCGgga |
hydrolyzed DNA |
Zn2+ Yb3+ |
DNA phosphodiester | N 40 |
|---|
| Buffer conditions |
|---|
| 70 mM HEPES, pH 7.5, 150 mM NaCl, 1 mM ZnCl2, 10 µM YbCl3 |
| Yield (%) | kcat/ kobs |
|---|---|
| 25 | kobs = 0.055 h-1 |
| Catalytic region of the DNAzyme |
|---|
| TGGGGGCTAGCCGAGAGCAAAGCCATGCAAAACGAGGACC |
| Year of Publication | First Author | Laboratory | Title | PubMed ID | DOI | Reaction |
|---|---|---|---|---|---|---|
| 2012 | V Dokukin | S K Silverman | Lanthanide ions as required cofactors for DNA catalysts | None | 10.1039/C2SC01067D | DNA cleavage |